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khoom

Bet-thujaplicin CAS Nr 499-44-5

Chemical Property:

Molecular Formula C10H12O2
Molar Mass 164.2 ib
Qhov ntom 1.0041 (zeeg)
Melting Point 50-52 ° C (lit.)
Boling Point 140 ° C 10 hli Hg (lit.)
Flash Point 128.1°C dej
Solubility Insoluble hauv dej
Vapor Siab 8.98E-05mmHg ntawm 25 ° C
Qhov tshwm sim Tsis muaj xim, prismatic crystals (recrystallized los ntawm anhydrous ethanol)
Xim Dawb
Merck 14, 9390 ib
pKa 7.06 ± 0.30 (Tshaj tawm)
Kev cia khoom Muab kaw rau hauv qhuav, Chav Kub
Kev ruaj ntseg ruaj khov rau 1 xyoo txij li hnub ntawm kev yuav khoom raws li muab. Kev daws teeb meem hauv DMSO lossis ethanol tuaj yeem khaws cia ntawm -20 ° txog li 4 lub hlis.
rhiab heev Tsis txhob kov cov oxides
Refractive Index 1.5190 (kwv yees)
MDL PAB 00059582
Kev tshawb nrhiav hauv vitro Hauv U87MG thiab T98G glioma cell kab, hinokitiol ua kom pom qhov txo qis ntawm qhov muaj peev xwm, nrog IC 50 qhov tseem ceeb ntawm 316.5 ± 35.5 thiab 152.5 ± 25.3 µM, feem. Hinokitiol txwv tsis pub ALDH kev ua haujlwm thiab kev muaj peev xwm rov ua dua nws tus kheej hauv glioma qia hlwb, thiab inhibits hauv vitro oncogenicity. Hinokitiol kuj txo Nrf2 kev qhia hauv glioma qia hlwb nyob rau hauv koob tshuaj. Hinokitiol (0-100 μM) inhibits qog nqaij hlav qog noj ntshav hauv cov koob tshuaj thiab lub sijhawm nyob ntawm lub sijhawm. Hinokitiol (5, 10 μM) txo DNMT1 thiab UHRF1 mRNA thiab protein qhia, thiab nce TET1 qhia los ntawm kev txhim kho ntawm 5hmC qib hauv HCT-116 hlwb. Tsis tas li ntawd, hinokitiol txo qis methylation raws li txoj cai thiab rov kho mRNA qhia ntawm MGMT, CHST10, thiab BTG4 noob.

Product Detail

Khoom cim npe

Hazard Cov Cim Xn – Ua phem
Risk Codes 22 – Ua phem yog nqos
Kev nyab xeeb piav qhia 36 – Hnav khaub ncaws tiv thaiv kom haum.
WGK Germany 3
RTECS GU4200000

 

Taw qhia

Hinokiol, tseem hu ua α-terpene cawv los yog Thujanol, yog ib qho organic compound uas yog ib qho ntawm cov khoom ntawm turpentine. Hinoylol yog cov xim tsis muaj xim, pob tshab kua nrog cov ntxhiab tsw qab.

 

Hinokiol muaj ntau yam kev siv. Nws yog dav siv hauv kev lag luam naj hoom thiab tshuaj tsw qab los ntxiv cov tshuaj tsw qab thiab tshuaj tsw qab rau cov khoom. Qhov thib ob, juniper cawv kuj yog siv los ua cov tshuaj tua kab mob thiab tshuaj tua kab mob, thiab feem ntau siv rau hauv kev npaj tshuaj tua kab mob thiab fungicides.

 

Muaj ntau ntau txoj hauv kev los npaj juniperol. Feem ntau, nws tuaj yeem muab rho tawm los ntawm distillation ntawm cov roj tsis hloov pauv los ntawm cov nplooj juniper lossis lwm cov nroj tsuag cypress, thiab tom qab ntawd sib cais thiab lim kom tau juniperol. Hinoki cawv kuj tseem tuaj yeem ua ke los ntawm cov tshuaj synthesis.

 

Cov ntaub ntawv kev nyab xeeb ntawm juniperol: Nws tsis muaj tshuaj lom thiab feem ntau suav tias muaj kev nyab xeeb. Raws li cov organic compound, nws tseem yuav tsum tau ua thiab khaws cia kom raug. Tsis txhob sib cuag nrog daim tawv nqaij thiab qhov muag, thiab yaug nrog dej tam sim ntawd thaum muaj kev sib cuag tsis raug. Nws yuav tsum tau khaws cia kom deb ntawm cov nplaim taws thiab qhov kub thiab txias, thiab khaws cia rau hauv qhov chaw txias, qhuav.


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