1-(3-Hydroxymethylpyridin-2-yl)-4-methyl-2-phenylpiperazine CAS 61337-89-1
1-(3-Hydroxymethylpyridin-2-yl)-4-methyl-2-phenylpiperazine CAS 61337-89-1 qhia
Lub cev
Qhov tshwm sim: Raws li ib txwm muaj, nws yuav yog cov khoom siv crystalline, tab sis cov khoom siv lead ua morphology, xim thiab lwm yam ntsiab lus yuav tsum tau ua ke nrog kev soj ntsuam ntau dua thiab cov ntaub ntawv sau kom raug. Cov tsos ntawm cov khoom txiav txim siab seb nws ua haujlwm li cas thaum khaws cia, thauj thiab nkag mus, piv txwv li, crystalline solids yog qhov tsim nyog rau kev siv nrog spatula.
Solubility: Nyob rau hauv cov organic solvents, xws li ethanol thiab methylene chloride, nws yuav muaj ntau yam solubility. Cov ntaub ntawv solubility nyob rau hauv cov kuab tshuaj organic yog qhov tseem ceeb heev rau cov organic synthesis thwmsim siv nws los ua raw khoom los yog nruab nrab, kom cov kws tshawb fawb tuaj yeem tshuaj xyuas cov tshuaj tiv thaiv cov kuab tshuaj uas tsim nyog los xyuas kom meej tias cov tshuaj tiv thaiv tau ua tiav zoo ib yam thiab ua tau zoo.
Synthesis method
Pyridine thiab piperazine derivatives feem ntau yog siv los ua cov ntaub ntawv pib, thiab cov tshuaj organic xws li nucleophilic hloov pauv thiab condensation yog siv los tsim cov molecular molecular. Piv txwv li, pyridine derivatives uas tsim nyog pab pawg neeg tiv thaiv thawj zaug undergo nucleophilic hloov cov tshuaj tiv thaiv nrog activated piperazine precursors nyob rau hauv alkaline tej yam kev mob los tsim intermediates tseem ceeb; Tom qab ntawd, tom qab xaiv qhov kev tiv thaiv thiab cov kauj ruam hydroxymethylation, cov khoom lag luam tuaj yeem tau txais. Tag nrho cov txheej txheem synthesis yuav tsum muaj kev tswj xyuas nruj ntawm cov tshuaj tiv thaiv kub, cov tshuaj tiv thaiv lub sijhawm thiab cov khoom sib piv, thiab qhov sib txawv me ntsis yuav ua rau impurities, cuam tshuam rau purity thiab tawm los ntawm cov khoom.
siv
Pharmaceutical R & D: Nws cov qauv molecular tshwj xeeb ua ke nrog cov pab pawg nquag xws li pyridine thiab piperazine, qhia cov yam ntxwv ntawm kev ua cov tshuaj muaj peev xwm ua cov tshuaj lead. Cov pab pawg no tuaj yeem cuam tshuam tshwj xeeb nrog cov hom phiaj tshwj xeeb, xws li qee yam neurotransmitter receptors, hauv cov kab mob muaj sia, muab cov qauv qauv tshiab rau kev tsim cov tshuaj tshiab rau kev kho mob ntawm cov kab mob neurological thiab cov kab mob puas hlwb. Cov kws tshawb nrhiav yuav hloov kho nws cov qauv thiab sim nws cov haujlwm kom txuas ntxiv tshawb nrhiav nws cov peev txheej tshuaj.
Organic Building Blocks: Nyob rau hauv tag nrho cov synthesis ntawm complex organic molecules, nws yog ib tug high-zoo tsev thaiv. Cov kws kho mob tuaj yeem siv lawv qhov chaw ua haujlwm los txuas ntau pab pawg ua haujlwm kom txuas ntxiv molecular carbon chains thiab tsim ntau lub nplhaib, qhib cov tswv yim synthesis thiab chaw ua haujlwm rau kev tsim cov organic tebchaw nrog cov qauv tshiab thiab cov haujlwm tshwj xeeb.