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khoom

1-Boc-3-piperidone CAS 98977-36-7

Chemical Property:

Molecular Formula C10H17NO3
Molar Mass 199.25 Nws
Qhov ntom 1.099 ± 0.06 g / cm3 (Kev kwv yees)
Melting Point 35-40 ° C (lit.)
Boling Point 289.8 ± 33.0 ° C (Tshaj tawm)
Flash Point > 230 ° F
Dej Solubility Nws yog insoluble hauv dej.
Vapor Siab 0.002mmHg ntawm 25 ° C
Qhov tshwm sim Dawb khoom
Xim Ntshiab xim tsis muaj xim
BRN 5936353 ib
pKa -1.71 ± 0.20 (Kev kwv yees)
Kev cia khoom 2-8 ° C
Refractive Index 1.481 ib

Product Detail

Khoom cim npe

Risk thiab Safety

Kev nyab xeeb piav qhia 24/25 - Tsis txhob sib cuag nrog daim tawv nqaij thiab qhov muag.
WGK Germany 3
HS Code 29339900 ib
Hazard Class Cia txias

Cov ntaub ntawv siv

Taw qhia n-tert-butoxycarbonyl-3-piperidone yog ib qho tshuaj tua kab tseem ceeb, nws kuj yog ib qho nruab nrab rau cov tshuaj intermediates thiab lwm yam tshuaj additives. Muaj ntau txoj kev siv hluavtaws uas twb muaj lawm: (1) siv γ-butyrolactone ua raw khoom, tom qab benzylaminolysis, hydrolysis, esterification, condensation nrog ethyl bromoacetate, cyclization, 6-kauj ruam ntawm hydrolytic decarboxylation tsim 1-benzyl-3-piperidone hydrochloride, ua raws li debenzylation ntawm pawg tert-butoxycarbonyl muab n-tert-butoxycarbonyl-3-piperidone (US0053565). (2) nrog 3-hydroxypyridine ua raw khoom, cov tshuaj tiv thaiv nrog benzyl bromide los tsim quaternary ammonium ntsev, sodium borohydride txo, Palladium carbon debenzyl ntawm tert-butoxycarbonyl, N-tert-butoxycarbonyl-3-piperidone (CN103204801) tau txais los ntawm qis kub oxidation ntawm dimethyl sulfoxide.
Daim ntawv thov n-tert-butoxycarbonyl-3-piperidone yog ib qho nruab nrab ntawm cov organic synthesis thiab ib qho nruab nrab hauv cov tshuaj, tuaj yeem siv rau hauv kev tshawb fawb thiab kev loj hlob ntawm cov txheej txheem tshuaj thiab tshuaj synthesis txheej txheem, feem ntau yog siv rau kev tswj lub tso suab synthesis ntawm chiral compounds.
Siv N-tert-butoxycarbonyl-3-piperidone yog siv rau stereologically tswj synthesis ntawm chiral compounds.

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