1-Phenyl-3,4-dihydroisoquinoline (CAS # 52250-50-7)
1-Phenyl-3,4-dihydroisoquinoline (CAS # 52250-50-7)
1-Phenyl-3,4-dihydroisoquinoline, CAS naj npawb 52250-50-7, tau qhia tshwj xeeb ntxim nyiam nyob rau hauv chemistry thiab tshuaj.
Los ntawm cov tshuaj muaj txiaj ntsig, nws cov molecule tau ntse ua ke nrog cov txheej txheem xws li phenyl pawg thiab dihydroisoquinoline nplhaib, thiab qhov tshwj xeeb atomic kev sib txuas hom no tsim ib qho tshwj xeeb electron huab faib, uas tsim nws cov tshuaj tshwj xeeb thiab kev ruaj ntseg. Nyob rau hauv tsos, nws yog feem ntau yog nthuav raws li ib tug khoom nrog ib tug tej yam crystalline daim ntawv, cov xim yog feem ntau yog dawb los yog tawm-dawb, thiab cov siv lead ua qauv yog tsis tu ncua thiab kom, uas yog conducive rau purification thiab refining los ntawm recrystallization. Nyob rau hauv cov nqe lus ntawm solubility, nws qhia tau hais tias ib tug tej yam dissolution qauv nyob rau hauv cov organic solvents xws li ethanol thiab acetone, tab sis lub solubility nyob rau hauv dej yog kuj tsawg, uas yog ze ze rau lub polarity ntawm lub molecule, thiab kuj muab lub hauv paus rau kev xaiv ntawm Cov kuab tshuaj rau kev sib cais tom qab thiab kev sib xyaw ua ke.
Nyob rau hauv cov nqe lus ntawm kws tshuaj R & D zeem muag, nws muaj peev xwm ua rau lom. Cov qauv tshuaj ntawm cov khoom lag luam zoo ib yam li qee cov khoom lag luam pharmacologically nquag, qhia tias nws yuav muaj lub hom phiaj zoo sib xws. Kev tshawb fawb ua ntej qhia tau hais tias nws yuav muaj kev cuam tshuam rau cov kab mob neurological signaling pathways, thiab xav tias yuav koom nrog kev tsim cov tshuaj tshiab rau cov kab mob neurodegenerative, xws li Alzheimer's kab mob thiab Parkinson's kab mob, los ntawm kev tswj cov kab mob neurotransmitter txawv txav thiab inhibiting hyperapoptosis ntawm paj hlwb. Nyob rau tib lub sijhawm, hauv kev tiv thaiv qog nqaij hlav, cov pab pawg nquag hauv nws cov qauv tuaj yeem cuam tshuam nrog kev loj hlob, kev tsiv teb tsaws thiab kev cuam tshuam ntawm cov qog hlwb, qhib cov tswv yim tshiab rau kev kho mob qog noj ntshav, tau kawg, cov no tseem nyob rau thaum ntxov. theem ntawm kev tshawb fawb hauv chaw soj nstuam, thiab tseem muaj ntau txoj haujlwm tshawb fawb yuav tsum tau ua ua ntej daim ntawv thov kev kho mob.
Los ntawm qhov kev xav ntawm kev lag luam synthesis, cov txheej txheem organic chemical synthesis tam sim no tsuas yog tso siab rau, pib los ntawm cov ntaub ntawv yooj yim, los ntawm cov txheej txheem ntau yam los tsim cov pob txha molecular complex, cov txheej txheem cuam tshuam nrog cyclization, hloov pauv, condensation thiab lwm yam classical organic tshuaj tiv thaiv hom. , cov kws tshawb fawb txuas ntxiv txhim kho cov kev mob tshwm sim, txhim kho cov txiaj ntsig, txo cov nqi, kom ua tau raws li cov kev xav tau ntawm kev tshawb nrhiav qhov tob thiab ua tau ntau lawm. Nrog rau kev sib koom ua ke ntawm cov thev naus laus zis hauv ntau thaj chaw, kev txhim kho tag nrho ntawm 1-Phenyl-3,4-dihydroisoquinoline yuav tsum ua kom nrawm, txhaj tshuaj tshiab rau hauv tib neeg kev noj qab haus huv thiab kev tshawb fawb thiab thev naus laus zis.
