1H-Pyrrolo [2 3-b]pyridine 6-methoxy- (CAS # 896722-53-5)

Taw qhia

6-methoxy-1H-cryrolo [2,3-b] pyridine yog cov organic compound nrog cov tshuaj formula C9H8N2O. Nws cov khoom yog raws li nram no:

1. Cov tsos mob: 6-methoxy-1H-chrrolo [2,3-b]pyridine tsis muaj xim rau daj siv lead ua.

2. melting point: txog 105-108 ℃.

3. Boiling point: txog 325 ℃.

4. Solubility: Nws yog soluble hauv organic solvents xws li chloroform, methanol thiab dimethyl sulfoxide, thiab me ntsis soluble hauv dej.

6-methoxy-1H-yrrolo [2,3-b]pyridine muaj kev siv tseem ceeb hauv kev tshawb fawb tshuaj thiab tshuaj, xws li:

1. Kev kho tshuaj: Nws yog dav siv nyob rau hauv kev tshawb fawb thiab kev loj hlob ntawm kev tiv thaiv qog, tiv thaiv kab mob, tiv thaiv qog noj ntshav thiab lwm yam tshuaj.

2. Chemical synthesis: Ua ib qho tseem ceeb nruab nrab ntawm cov organic synthesis, nws tuaj yeem siv los tsim cov txheej txheem organic molecular.

Txoj kev npaj 6-methoxy-1H-cryrolo [2,3-b] pyridine yog cov hauv qab no:

1. N-methylation cov tshuaj tiv thaiv ntawm indole: Indole yog reacted nrog methyl halide los tsim 6-methyl indole, thiab ces reacted nrog N-methyl vinyl amine los tsim 6-methoxy-1H-cryrolo [2,3-b]pyridine.

2. Redox cov tshuaj tiv thaiv ntawm indole: 6-methoxy-1H-pyridolo [2,3-b]pyridine tuaj yeem tau los ntawm kev ua haujlwm indole nrog sodium nitrite thiab tert-butyl peroxide.

Hais txog kev nyab xeeb cov ntaub ntawv, muaj ob peb txoj kev tshawb fawb txog kev toxicity thiab txaus ntshai ntawm 6-methoxy-1H-pyridolo [2,3-b]pyridine, yog li kev ntsuam xyuas tshwj xeeb ntawm kev nyab xeeb xav tau kev tshawb fawb ntxiv. Thaum ua cov kev sim lossis kev siv, kev sim ua kom raug thiab ntsuas kev nyab xeeb yuav tsum tau ua raws li, tsis txhob sib cuag nrog cov tawv nqaij thiab qhov muag, ua tib zoo saib xyuas kev tiv thaiv, thiab tsis txhob nqus cov aerosols lossis hmoov av. Yog tias tsim nyog, nws yuav tsum tau siv nyob rau hauv qhov chaw zoo ventilated.