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2-Amino-6-bromopyridine (CAS # 19798-81-3) Featured duab
  • 2-Amino-6-bromopyridine (CAS # 19798-81-3) 1

2-Amino-6-bromopyridine (CAS # 19798-81-3)

Chemical Property:

Molecular Formula C5H5BrN2
Molar Mass 173.01 Nws
Qhov ntom 1.710 ± 0.06 g / cm3 (Kev kwv yees)
Melting Point 88-91 ° C (lit.)
Boling Point 273.0 ± 20.0 ° C (Kev kwv yees)
Flash Point 118.9°C dej
Dej Solubility Me ntsis soluble hauv dej.
Solubility Chloroform (me ntsis), Methanol (Muaj me ntsis)
Vapor Siab 0.0059mmHg ntawm 25 ° C
Qhov tshwm sim Dawb rau brownish xim av hmoov
Xim Me ntsis daj rau lub teeb xim av
pKa 2.73 ± 0.24 (Tshaj tawm)
Kev cia khoom Khaws nyob rau hauv qhov chaw tsaus, kaw hauv qhuav, Chav Kub

Product Detail

Khoom cim npe

Risk thiab Safety

Risk Codes R36/37/38 - Kab mob rau qhov muag, ua pa thiab tawv nqaij.
R20/21/22 - Ua phem los ntawm kev nqus pa, tiv thaiv daim tawv nqaij thiab yog tias nqos.
Kev nyab xeeb piav qhia S26 - Thaum sib cuag nrog lub qhov muag, yaug tam sim ntawd nrog dej txaus thiab nrhiav kev kho mob.
S36 - Hnav khaub ncaws tiv thaiv zoo.
S36/37/39 - Hnav cov khaub ncaws tiv thaiv tsim nyog, hnab looj tes thiab tiv thaiv qhov muag / ntsej muag.
WGK Germany 3
HS Code 2933399 ib
Hazard Class IRRITANT

 

 

2-Amino-6-bromopyridine (CAS # 19798-81-3) Cov ntaub ntawv

Txheej txheem cej luam 2-amino hloov pauv nitrogen-muaj rau-tus tswv cuab heterocyclic tebchaw muaj cov ntawv thov tseem ceeb hauv kev lag luam tshuaj, xws li 2-amino -6-Bromopyridine yog ib qho ntawm cov qauv tseem ceeb hauv cov tshuaj hluavtaws thiab cov tshuaj lom neeg ua liaj ua teb, thiab tau siv dav hauv kev tsim khoom. ntawm cov khoom ntuj, tshuaj, cov ntaub ntawv luminescent thiab ntau yam tshuaj zoo.
Daim ntawv thov 2-amino hloov nitrogen-muaj rau-membed heterocyclic tebchaw muaj cov ntaub ntawv tseem ceeb hauv kev lag luam tshuaj, xws li 2-amino -6-Bromopyridine yog ib qho ntawm cov qauv tseem ceeb hauv cov tshuaj hluavtaws thiab cov tshuaj lom neeg ua liaj ua teb, thiab tau siv dav hauv cov khoom siv hluavtaws. ntawm cov khoom ntuj, tshuaj, cov ntaub ntawv luminescent thiab ntau yam tshuaj zoo.
Kev npaj Kev npaj ntawm 2-amino-6-bromopyridine: Ntxiv 2-fluoro-6-bromo-pyridine (1mmol), pentamidine hydrochloride (2mmol), sodium tert-butoxide (3mmol), HO (0.5mL) thiab diethylene glycol dimethyl ether (2.5). mL) hauv 25 ml cov tshuaj tiv thaiv raj. Cov tshuaj tiv thaiv tau ua tiav ntawm 150 ℃ rau 24 teev. Tom qab cov tshuaj tiv thaiv tiav lawm, nws tau txias rau chav sov. Ntxiv 10mL ntawm ethyl acetate los tua cov tshuaj tiv thaiv, ntxiv 6mL dej ntsev ntsev kom ntxuav, cais cov organic theem, ces rho tawm cov theem aqueous nrog ethyl acetate rau 3 zaug (qhov ntau npaum ntawm ethyl acetate txhua zaus yog 6mL) thiab muab cov organic. theem, ntxiv anhydrous sodium sulfate kom qhuav, tshem tawm cov hnyav nrog rau cov kuab tshuaj organic thiab inorganic hnyav los ntawm lub tshuab nqus tsev. distillation, thiab tom qab ntawd cais cov organic hnyav los ntawm kab chromatography kom tau cov khoom lag luam 2-amino-6-bromopyridine nrog cov txiaj ntsig ntawm 93%.
siv tshuaj intermediates.
rau cov synthesis zoo ntawm 7-azafindole hauv ib lub lauj kaub; rau cov synthesis ntawm cov tshuaj tiv thaiv kab mob HIV

 

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