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2-Bromo-5-(trifluoromethyl) pyridine (CAS # 50488-42-1)

Chemical Property:

Molecular Formula C6H3BrF3N
Molar Mass 225.99 Nws
Qhov ntom 1.707 ± 0.06 g / cm3 (Tshaj tawm)
Melting Point 44-48 ° C
Boling Point 78 ° C
Flash Point 78-81 ° C / 30 hli
Solubility Soluble hauv methanol thiab ethanol.
Vapor Siab 0 mmHg ntawm 25 ° C
Qhov tshwm sim Ci daj koob
pKa -1?+-.0.10(Thov)
Kev cia khoom Khaws nyob rau hauv qhov chaw tsaus, kaw hauv qhuav, Chav Kub
Refractive Index 1.572 ib
MDL PAB 00153086
Physical thiab Chemical Properties Off-dawb crystals
Siv Substrate rau palladium-catalyzed α-arylation ntawm Refomatsky reagents

Product Detail

Khoom cim npe

Risk Codes R25 - Toxic yog nqos
R36/37/38 - Kab mob rau qhov muag, ua pa thiab tawv nqaij.
R20/21/22 - Ua phem los ntawm kev nqus pa, tiv thaiv daim tawv nqaij thiab yog tias nqos.
Kev nyab xeeb piav qhia S26 - Thaum sib cuag nrog lub qhov muag, yaug tam sim ntawd nrog dej txaus thiab nrhiav kev kho mob.
S36/37/39 - Hnav cov khaub ncaws tiv thaiv tsim nyog, hnab looj tes thiab tiv thaiv qhov muag / ntsej muag.
S22 - Tsis txhob nqus plua plav.
S36 - Hnav khaub ncaws tiv thaiv zoo.
UN IDs UN 2811 6.1/PG 3
WGK Germany 3
HS Code 293339 0
Hazard Class IRRITANT
Packing Group

 

Taw qhia

2-Bromo-5-(trifluoromethyl) pyridine (tseem hu ua BTFP) yog cov organic compound. Cov hauv qab no yog kev qhia txog nws qhov xwm txheej, kev siv, kev npaj thiab cov ntaub ntawv kev nyab xeeb:

 

Zoo:

- Zoo li: Dawb khoom

Molecular Luj: 206.00 g / mol

- Solubility: BTFP yooj yim soluble hauv cov kuab tshuaj organic (xws li cawv, ethers, ketones) tab sis tsawg soluble hauv dej.

 

Siv:

- Raws li kev sib txuas nruab nrab: BTFP tau siv dav hauv kev npaj cov organic synthesis intermediates, xws li pyridine compounds, aromatic compounds, thiab lwm yam.

- Raws li ligand: BTFP tuaj yeem siv los ua ligand rau hlau complexes thiab koom nrog ntau yam catalytic cov tshuaj tiv thaiv thiab kev npaj cov khoom siv.

- Raws li ib tug reagent: BTFP plays lub luag hauj lwm tseem ceeb nyob rau hauv cov organic synthesis, xws li coupling cov tshuaj tiv thaiv, hloov cov tshuaj tiv thaiv, thiab txo cov tshuaj tiv thaiv.

 

Txoj kev:

2-Bromo-5-(trifluoromethyl) pyridine tuaj yeem ua ke los ntawm cov kauj ruam hauv qab no:

1. Dissolve 2-amino-5-(trifluoromethyl) pyridine nyob rau hauv cov organic hnyav, xws li cawv los yog ketone.

2. Ntxiv cov tshuaj bromine (xws li hydrogen bromide, methyl bromide).

3. Ua cov tshuaj tiv thaiv ntawm qhov kub thiab txias thiab nplawm.

4. Lim cov khoom thiab nqa tawm crystallization thiab purification.

 

Cov ntaub ntawv kev nyab xeeb:

- BTFP tuaj yeem ua kom khov lossis crystallize ntawm qhov kub thiab txias, thov khaws cia ntawm chav tsev kub thiab tsis txhob crystallization.

- Hnav cov hnab looj tes thiab tsom iav uas tsim nyog thaum ua haujlwm kom tsis txhob sib cuag nrog daim tawv nqaij thiab qhov muag.

- Tsis txhob nqus nws cov plua plav lossis vapors, vim tias BTFP tuaj yeem ua rau muaj kev cuam tshuam rau kev ua pa.

- Xa mus rau phau ntawv qhia txog kev nyab xeeb thaum siv lossis tuav BTFP, thiab pov tseg cov khib nyiab thiab cov kuab tshuaj kom tsim nyog.


  • Yav dhau los:
  • Tom ntej:

  • Sau koj cov lus ntawm no thiab xa tuaj rau peb