2-Chloro-3-fluoro-6-picoline (CAS # 374633-32-6)
Taw qhia
Cov tsos mob: Feem ntau tsis muaj xim rau cov kua daj daj, cov yam ntxwv zoo li no txhais tau hais tias nws yuav nkag siab rau lub teeb thiab kub, thiab nws yuav tsum tau ntsuas kom tsis txhob muaj lub teeb thiab kub tswj thaum khaws cia thiab thauj mus los, xws li siv lub raj mis xim av thiab khaws cia. nyob rau hauv ib tug txias warehouse kom tsis txhob ntxiv xim tob tob thiab deterioration.
Solubility: Lub compound muaj zoo solubility nyob rau hauv cov organic solvents, xws li toluene thiab dichloromethane, ua raws li lub hauv paus ntsiab lus ntawm solubility zoo sib xws, thiab muaj ib tug affinity nrog organic solvents los ntawm tsim nyog ntawm hydrophobic ib feem ntawm lub molecule; Txawm li cas los xij, solubility hauv dej yog tsawg, thiab muaj zog hydrogen sib txuas ntawm cov dej molecules yog qhov nyuaj rau kev tawg ntawm cov molecule, ua rau nws nyuaj rau disperse nws.
Boiling point and density: Boiling point data is closely related to its volatility and can provide the key parameters for operations such as distillation and purification, tab sis hmoov tsis txog qhov tshwj xeeb boiling point tus nqi tseem tsis tau nthuav dav dav. Nws qhov ntom yog me ntsis siab dua li cov dej, thiab kev nkag siab qhov ceev tuaj yeem pab kom raug kwv yees qhov ntim-mas hloov pauv kev sib raug zoo hauv kev sim ua haujlwm lossis cov txheej txheem kev lag luam xws li cov kua hloov pauv thiab kev ntsuas qhov tseeb.
Cov khoom siv tshuaj
Hloov cov tshuaj tiv thaiv: Cov tshuaj chlorine atom thiab fluorine atom nyob rau hauv lub molecule yog qhov chaw reactive. Hauv cov tshuaj tiv thaiv nucleophilic hloov pauv, cov nucleophiles muaj zog tuaj yeem tua cov chaw uas cov tshuaj chlorine thiab fluorine atoms nyob, hloov cov atoms sib xws, thiab tsim cov pyridine derivatives tshiab. Piv txwv li, nws tau ua ke nrog ib co nitrogen-muaj thiab sulfur-muaj nucleophiles los tsim ib tug series ntawm nitrogen-muaj heterocyclic tebchaw nrog ntau complex qauv rau cov tshuaj nrhiav los yog cov khoom siv synthesis.
Cov tshuaj tiv thaiv Redox: lub nplhaib pyridine nws tus kheej yog qhov ruaj khov, tab sis thaum muaj zog oxidants, xws li poov tshuaj permanganate thiab hydrogen peroxide yog txuam nrog acidic tej yam kev mob, oxidation yuav tshwm sim, ua rau kev puas tsuaj los yog hloov kho ntawm pyridine nplhaib qauv; Conversely, nrog ib tug tsim nyog txo tus neeg sawv cev, xws li hlau hydrides, nws yog theoretically ua tau rau hydrogenation ntawm intramolecular unsaturated bonds.
Plaub, txoj kev synthesis
Txoj kev sib xyaw ua ke yog pib los ntawm cov pyridine derivatives yooj yim thiab maj mam tsim lub hom phiaj los ntawm halogenation thiab fluorination cov tshuaj tiv thaiv. Cov khoom pib pyridine tebchaw yog thawj zaug xaiv methylated thiab cov methyl pawg tau qhia tib lub sijhawm; Tom qab ntawd siv halogenation reagents, xws li cov tshuaj chlorine thiab kua chlorine, nrog rau cov catalysts thiab cov tshuaj tiv thaiv, kom ua tiav cov kev taw qhia ntawm chlorine atoms; Thaum kawg, fluorinated reagents, xws li Selectfluor, tau siv los ua kom raug fluorinate lub hom phiaj kom tau 2-chloro-3-fluoro-6-methylpyridine.
Siv
Cov tshuaj synthesis intermediates: nws cov qauv tshwj xeeb yog nyiam los ntawm cov kws kho mob tshuaj, thiab nws yog ib qho zoo nruab nrab rau kev tsim cov tshuaj tua kab mob tshiab, tshuaj tua kab mob, thiab tshuaj tua kab mob. Cov khoom siv hluav taws xob thiab cov qauv spatial ntawm pyridine rings thiab lawv cov khoom hloov pauv tshwj xeeb tuaj yeem khi rau lub hom phiaj cov proteins hauv vivo, thiab xav tias yuav hloov mus rau hauv cov khoom xyaw nquag nrog cov txiaj ntsig zoo tom qab kev hloov kho ntau kauj ruam.
Cov ntaub ntawv tshawb fawb: Hauv kev ua haujlwm ntawm cov khoom siv organic synthesis, nws tuaj yeem siv los tsim cov khoom siv polymer, cov ntaub ntawv fluorescent, thiab lwm yam, los ntawm kev tsim txiaj ntawm nws lub peev xwm los qhia meej chlorine, fluorine atoms thiab pyridine cov qauv, endow cov ntaub ntawv nrog tshwj xeeb hluav taws xob thiab kho qhov muag. cov khoom, thiab txhawb txoj kev loj hlob ntawm kev siv thev naus laus zis xws li cov ntaub ntawv ntse thiab cov khoom siv.
