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2-(chloromethyl)-5-(trifluoromethyl)-1 3 4-oxadiazole (CAS # 723286-98-4)

Chemical Property:

Molecular Formula C4H2ClF3N2O
Molar Mass 186.52 Nws
Qhov ntom 1.555 ± 0.06 g / cm3 (Kev kwv yees)
Boling Point 55-60 ° C (Nias: 10 Torr)
Flash Point 41.1°C dej
Solubility Chloroform (Soluble), Methanol (Sparingly)
Vapor Siab 6.44mmHg ntawm 25 ° C
Qhov tshwm sim Roj
Xim Pleev daj rau daj
pKa -8.11 ± 0.44 (Tshaj tawm)
Kev cia khoom Khaws nyob rau hauv qhov chaw tsaus, Inert cua, Khaws rau hauv lub freezer, hauv qab -20 ° C
Refractive Index 1.406 ib

Product Detail

Khoom cim npe

 

Taw qhia

2-(chloromethyl)-5-(trifluoromethyl)-1,3,4-oxadiazole yog cov organic compound nrog cov mis mos C4H2ClF3N2O.

 

Xwm:

2-(chloromethyl)-5-(trifluoromethyl)-1,3,4-oxadiazole yog cov xim tsis muaj xim rau cov kua daj daj lossis crystalline khoom. Nws muaj siab thermal stability thiab tshuaj inertness. Nws yog insoluble nyob rau hauv dej ntawm chav tsev kub, soluble nyob rau hauv ib co organic solvents xws li ethanol thiab ether. Lub compound tuaj yeem ua tus cwj pwm los ntawm cov txheej txheem xws li nuclear magnetic resonance thiab huab hwm coj spectrometry.

 

Siv:

2-(chloromethyl)-5-(trifluoromethyl)-1,3,4-oxadiazole muaj qee yam nqi siv rau hauv kev lag luam chemistry. Nws feem ntau yog siv los ua ib qho nruab nrab hauv cov organic synthesis rau cov synthesis ntawm lwm cov tebchaw. Tsis tas li ntawd, nws kuj yog siv los ua kev tshawb fawb reagent hauv thaj chaw tshuaj tua kab thiab tshuaj.

 

Txoj Kev Npaj:

2-(chloromethyl)-5-(trifluoromethyl)-1,3,4-oxadiazole tuaj yeem ua ke los ntawm ntau txoj kev. Cov hauv qab no yog ib txoj kev npaj ntau:

 

1. Ntxiv ib qho catalyst (xws li triethylamine) rau lub cev tsis muaj dej tsis haum cov tshuaj tiv thaiv kab mob.

2. Ntxiv ib qho nyiaj ntawm methyl 3-chloropropionate thiab methyl trifluoroformate rau lub cev hnyav.

3. Cov tshuaj tiv thaiv yog nqa tawm ntawm qhov tsim nyog kub nyob rau hauv ib qho chaw inert, thiab feem ntau nws yog tsim nyog los ua kom sov cov tshuaj tiv thaiv sib tov.

4. Lim los yog distillation kom tau txais cov khoom, tom qab tsim nyog purification thiab ziab kom tau cov khoom ntshiab.

 

Cov ntaub ntawv kev nyab xeeb:

2-(chloromethyl)-5-(trifluoromethyl)-1,3,4-oxadiazole feem ntau muaj kev nyab xeeb thaum siv thiab khaws cia kom raug. Txawm li cas los xij, raws li cov organic compound, nws yuav ua rau muaj kev phom sij rau tib neeg kev noj qab haus huv thiab ib puag ncig. Hauv kev siv thiab tuav, yuav tsum ua raws li cov txheej txheem kev nyab xeeb kom raug, thiab zam kev sib cuag ncaj qha. Cov lus qhia txog kev nyab xeeb rau qhov sib xyaw yuav tsum tau ua tib zoo nyeem thiab ua raws. Yog tias tsim nyog, kev ua haujlwm yuav tsum tau ua raws li kev coj ua ntawm cov neeg ua haujlwm tshaj lij.


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  • Sau koj cov lus ntawm no thiab xa tuaj rau peb