2-(DIPHENYLMETHYL)-QUINUCLIDIN-3-ONE CAS #32531-66-1

2-(DIPHENYLMETHYL)-QUINUCLIDIN-3-ONE, CAS NO 32531-66-1, muaj ntau yam txaus siab rau hauv CHEMISTRY thiab cov ntawv thov cuam tshuam.

Los ntawm kev tshuaj xyuas ntawm cov qauv tshuaj, nws qhov tshwj xeeb molecular architecture fuses cov qauv ntawm diphenyl methyl thiab quinine. Diphenyl methyl pawg coj ib tug loj steric hindrance thiab conjugation system, uas cuam tshuam rau lub electron huab ntws ntawm lub molecule, thaum lub quinine cyclic ketone ib feem muab cov molecule tej yam nruj thiab yooj yim yam ntxwv, thiab ob synergistically tsim ib tug kuj ruaj khov tab sis reactive tshuaj qauv. Feem ntau nyob rau hauv daim ntawv ntawm cov hmoov dawb crystalline hmoov, daim ntawv no ua kom yooj yim khaws cia, kev thauj mus los, thiab kev tsim cov txheej txheem tom ntej. Nyob rau hauv cov nqe lus ntawm solubility, nws muaj zoo solubility nyob rau hauv non-polar organic solvents xws li benzene thiab toluene, uas yog vim lub non-polar cheeb tsam ntawm lub molecule, thaum nws muaj tsis zoo solubility nyob rau hauv ntau polar solvents xws li dej thiab cawv, uas. Nws yog ib qho tseem ceeb heev rau kev xaiv cov kuab tshuaj, kev sib cais thiab kev ua kom huv hauv cov tshuaj synthesis.
Hais txog kev siv tshuaj kho mob muaj peev xwm, nws cov qauv zoo ib yam li qee cov tshuaj psychotropic uas twb muaj lawm, qhia tias nws tuaj yeem ua rau lub hauv paus paj hlwb ntsig txog lub hom phiaj. Cov kev tshawb fawb thaum ntxov tau pom tias nws yuav muaj kev tswj hwm ntawm kev nce thiab tso tawm ntawm cov neurotransmitters, thiab xav tias yuav siv los kho cov kab mob puas siab puas ntsws xws li schizophrenia thiab kev nyuaj siab, thiab txhim kho cov neeg mob cov tsos mob los ntawm kev cuam tshuam cov paj hlwb tsis zoo. Txawm li cas los xij, tam sim no, feem ntau ntawm lawv yog nyob rau theem ntawm kev sim ntawm tes thiab kev tshawb nrhiav tsiaj, thiab tseem muaj txoj hauv kev mus ntev ua ntej lawv dhau los ua cov tshuaj kho mob, thiab nws yog ib qho tsim nyog yuav tsum tshawb xyuas lawv cov tshuaj pharmacological, cov tshuaj lom neeg, pharmacokinetics thiab ntau lwm yam.
Los ntawm txoj kev xav ntawm cov txheej txheem synthesis, nws tsuas yog nyob ntawm txoj kev zoo organic synthesis. Pib nrog cov ntaub ntawv yooj yim thiab yooj yim muaj, lub hom phiaj molecule yog tsim los ntawm cov txheej txheem cov tshuaj tiv thaiv xws li cyclization, hloov pauv, thiab sib txuas. Cov kws tshawb fawb niaj hnub sim cov catalysts tshiab thiab cov tshuaj tiv thaiv kev tshaj tawm, ua kom zoo dua qhov kub thiab txias, lub sijhawm thiab lwm yam kev mob, thiab siv zog los txhim kho synthesis efficiency thiab txo cov nqi, thiaj li ua kom muaj peev xwm ua tau raws li kev tshawb fawb tob tob thiab muaj peev xwm tsim tau.