2-Methyl-4-trifluoromethyl-thiazole-5-carboxylic acid (CAS # 117724-63-7)
2-methyl -4-(trifluoromethyl) thiazole-5-carboxylic acid yog cov organic compound nrog cov tshuaj formula C6H4F3NO2S.
Lub compound muaj cov khoom nram qab no:
1. Cov tsos mob: tsis muaj xim tsis muaj xim lossis dawb crystalline hmoov.
2. Melting point: txog 70-73 ° C.
3. solubility: soluble nyob rau hauv ib co organic solvents, xws li ethanol, dimethyl sulfoxide thiab chloroform, me ntsis soluble nyob rau hauv dej.
2-methyl -4-(trifluoromethyl) thiazole-5-carboxylic acid lub ntsiab siv suav nrog:
1. Pharmaceutical teb: raws li cov tshuaj nruab nrab, tuaj yeem siv rau kev sib xyaw ntawm ntau yam tshuaj.
2. Tshuaj tua kab: feem ntau siv rau hauv kev sib txuas ntawm cov tshuaj tua kab tshiab, tshuaj tua kab thiab lwm yam tshuaj tua kab.
2-methyl -4-(trifluoromethyl) thiazole -5-carboxylic acid kev npaj yog cov hauv qab no:
1. amide thiab formaldehyde condensation cov tshuaj tiv thaiv: formic acid thiab ethyl ester condensation los tsim cov kua qaub anhydride, thiab tom qab ntawd nrog cov tshuaj tiv thaiv amine condensation kom tau txais cov khoom lag luam.
2. Hydrogenation cov tshuaj tiv thaiv nyob rau hauv acid catalysis: 2-methyl -4-(trifluoromethyl) thiazole-5-carboxylic acid yog reacted nrog hydrogen nyob rau hauv acid catalysis kom tau lub hom phiaj cov khoom.
Hais txog cov ntaub ntawv kev nyab xeeb, cov ntaub ntawv toxicological thiab kev nyab xeeb ntawm 2-methyl -4-(trifluoromethyl) thiazole-5-carboxylic acid tsis tshua muaj tshwm sim, yog li nws yuav tsum tau ua qee yam kev tiv thaiv kev nyab xeeb thaum ua haujlwm hauv chav kuaj, xws li hnav tsom iav thiab hnab looj tes, los xyuas kom meej tias qhov kev sim ua haujlwm tau ua nyob rau hauv ib qho chaw zoo-ventilated. Tsis tas li ntawd, qhov sib xyaw ua ke tuaj yeem ua rau corrosive thiab irritating, thiab yuav tsum tau saib xyuas kom tsis txhob sib cuag nrog daim tawv nqaij thiab nqus tau pa. Thaum siv thiab khaws cia, cov txheej txheem tshuaj lom neeg yuav tsum tau ua raws thiab khaws cia rau hauv qhov chaw qhuav, qhov cua thiab qhov chaw tsaus. Thaum tuav thiab pov tseg ntawm qhov sib xyaw no, ua raws li cov kev cai hauv zos thiab cov lus qhia ua haujlwm nyab xeeb. Yog tias koj tau ntsib nrog cov tshuaj no, yaug tam sim ntawd nrog dej ntau thiab nrhiav kev pab kho mob.
