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2- (trifluoromethyl) thiazole-4-carboxylic acid (CAS # 915030-08-9)

Chemical Property:

Molecular Formula C5H2F3NO2S
Molar Mass 197.14 Nws
Qhov ntom 1.668 ± 0.06 g / cm3 (Tshaj tawm)
Melting Point 179-184 ° C
Boling Point 224.6 ± 40.0 ° C (Tshaj tawm)
Flash Point 89.627°C dej
Vapor Siab 0.052mmHg ntawm 25 ° C
pKa 3.09 ± 0.10 (Kev kwv yees)
Kev cia khoom 2-8 ° C
Refractive Index 1.498 ib

Product Detail

Khoom cim npe

Hazard Cov Cim Xn – Ua phem
Risk Codes 22 – Ua phem yog nqos
WGK Germany 3
Hazard Class IRRITANT

 

Taw qhia

2-(trifluoromethyl) thiazole-4-carboxylic acid yog cov organic compound nrog cov tshuaj formula C5H2F3NO2S. Nws qhov xwm txheej, kev siv, kev tsim thiab kev nyab xeeb cov ntaub ntawv tau piav qhia hauv qab no.

 

Xwm:

2-(trifluoromethyl) thiazole-4-carboxylic acid yog dawb crystalline khoom. Nws tuaj yeem yaj hauv qee cov kuab tshuaj organic xws li dimethylsulfamide (DMSO) thiab carbon disulfide (CS2), tab sis yog insoluble hauv dej. Nws melting point yog hais txog 220-223 ° C.

 

Siv:

2-(trifluoromethyl) thiazole-4-carboxylic acid yog ib qho nquag siv organic synthesis nruab nrab. Nws tuaj yeem siv los ua ke qee cov tshuaj bioactive hauv thaj chaw tshuaj, xws li tshuaj thiab tshuaj tua kab. Tsis tas li ntawd, nws tseem tuaj yeem siv los ua cov khoom siv hluavtaws rau dyes thiab cov tshuaj photosensitive.

 

Txoj kev:

Kev npaj ntawm 2-(trifluoromethyl) thiazole-4-carboxylic acid feem ntau tau txais los ntawm cov tshuaj tiv thaiv ntawm methyl sulfide thiab cyanomethane. Cov kauj ruam tshwj xeeb yog raws li hauv qab no: ua ntej, 2-amino -1, 3-thiazole yog reacted nrog trifluoroacetaldehyde los tsim 2-(trifluoromethyl)-1, 3-thiazole; Tom qab ntawd, cov tau txais 2-(trifluoromethyl)-1, 3-thiazole yog reacted nrog cyanomethane los tsim lub hom phiaj cov khoom 2-(trifluoromethyl) thiazole-4-carboxylic acid.

 

Cov ntaub ntawv kev nyab xeeb:

Lub toxicity thiab txaus ntshai ntawm 2-(trifluoromethyl) thiazole-4-carboxylic acid tsis tau kawm tag. Txawm li cas los xij, raws li tshuaj lom neeg, kev coj ua kev nyab xeeb dav dav yuav tsum tau ua raws li, xws li hnav cov khoom tiv thaiv tsim nyog (xws li tsom iav, hnab looj tes thiab cov tsho hauv chav kuaj) thiab tuav hauv qhov chaw muaj cua zoo. Tom qab raug rau qhov sib xyaw no, thaj chaw cuam tshuam yuav tsum tau ntxuav tam sim nrog xab npum thiab dej. Yog tias tsim nyog, nrhiav kev kho mob rau kev tswj xyuas ntxiv.


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