3-Chloro-5-(trifluoromethyl) pyridine (CAS # 85148-26-1)
| Risk Codes | R20/21/22 - Ua phem los ntawm kev nqus pa, tiv thaiv daim tawv nqaij thiab yog tias nqos. R36/37/38 - Kab mob rau qhov muag, ua pa thiab tawv nqaij. R25 - Toxic yog nqos |
| Kev nyab xeeb piav qhia | S26 - Thaum sib cuag nrog lub qhov muag, yaug tam sim ntawd nrog dej txaus thiab nrhiav kev kho mob. S36/37/39 - Hnav cov khaub ncaws tiv thaiv tsim nyog, hnab looj tes thiab tiv thaiv qhov muag / ntsej muag. S36 - Hnav khaub ncaws tiv thaiv zoo. S45 - Thaum muaj xwm txheej lossis yog tias koj tsis xis nyob, nrhiav kev kho mob tam sim ntawd (qhia daim ntawv lo thaum twg ua tau.) |
| UN IDs | UN 2811 6.1 / PGIII |
| WGK Germany | 3 |
| Kev Ceeb Toom | Irritant |
| Hazard Class | IRRITANT, IRRITANT-H |
| Packing Group | III |
Taw qhia
3-choro-5-(trifluoromethyl)pyridine yog ib qho organic compound nrog cov tshuaj formula C≡H₂ ClFΛ N. Nws yog ib qho xim tsis muaj xim daj daj daj nrog cov ntxhiab tsw. Cov hauv qab no yog cov lus piav qhia ntawm qhov xwm txheej, kev siv, kev npaj thiab kev nyab xeeb ntawm 3-choro-5-(trifluoromethyl) pyridine:
Xwm:
Qhov ceev: 1.578 g / mL
- Kub taw tes: 79-82 ℃
- Melting point: -52.5 ℃
-Solubility: Soluble nyob rau hauv organic solvents xws li ethanol, ether thiab dichloromethane, me ntsis soluble nyob rau hauv dej.
Siv:
-As reagents thiab intermediates nyob rau hauv cov organic synthesis, siv nyob rau hauv synthesis ntawm tshuaj tua kab, tshuaj thiab lwm yam organic tebchaw.
-Rau kev tshawb fawb nyob rau hauv cov tshuaj, xws li nyob rau hauv cov synthesis ntawm anti-cancer tshuaj thiab biomarkers.
Txoj Kev Npaj:
3-chloro-5-(trifluoromethyl) pyridine tuaj yeem npaj tau los ntawm ob txoj hauv qab no:
1. Siv pyridine ua raw khoom, chlorination cov tshuaj tiv thaiv yog nqa tawm nyob rau hauv lub xub ntiag ntawm hydrochloric acid, thiab ces trifluoromethylation cov tshuaj tiv thaiv yog nqa tawm nyob rau hauv lub xub ntiag ntawm sodium trifluoromethylate.
2. Siv 3-picolinic acid ua raw khoom, chlorination cov tshuaj tiv thaiv yog nqa tawm nyob rau hauv lub xub ntiag ntawm thionyl chloride, thiab ces ib tug trifluoromethylation cov tshuaj tiv thaiv yog nqa tawm nyob rau hauv lub xub ntiag ntawm trifluoromethyl mercaptan.
Cov ntaub ntawv kev nyab xeeb:
- 3-chloro-5-(trifluoromethyl) pyridine ua rau khaus thiab tuaj yeem ua rau khaus ntawm daim tawv nqaij thiab qhov muag. Nws yog ib qho tsim nyog yuav tsum hnav cov kev tiv thaiv tsim nyog thaum siv, xws li hnav tsom iav tiv thaiv, hnab looj tes thiab khaub ncaws tiv thaiv.
-Tsis txhob nqus nws cov vapor thiab xyuas kom meej tias kev ua haujlwm tau ua nyob rau hauv qhov chaw muaj cua zoo.
-Thaum khaws cia, khaws cia rau hauv lub thawv kaw, kom deb ntawm hluav taws thiab oxidizing tus neeg sawv cev.
-Thaum muab pov tseg pov tseg, kho thiab pov tseg raws li cov cai hauv zos.
-Thov xyuas daim ntawv txheeb xyuas kev nyab xeeb (SDS) kom paub meej ntxiv txog kev nyab xeeb.
