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3-methyl-2-oxobutyric acid (CAS # 759-05-7)

Chemical Property:

Molecular Formula C5H8O3
Molar Mass 116.12 Nws
Qhov ntom 0.9968 ib
Melting Point 31.5 ℃
Boling Point 170.5 ℃
JECFA Number 631 ib
Dej Solubility 400.6g / L (20 ºC)
pKa 2.57 ± 0.54 (Tshaj tawm)
Kev cia khoom 2-8 ° C
Refractive Index 1.3850 Nws
Kev tshawb nrhiav hauv vitro 3-Methyl-2-oxobutanoic acid (alpha-Ketoisovaleric acid) yog ib qho precursor ntawm pantothenic acid hauv Escherichia coli. 3-Methyl-2-oxobutanoic acid (alpha-Ketoisovaleric acid) txhim kho alpha-ketoisocaproic acid thiab alpha-keto-beta-methyl-n-valeric acid, tab sis txo qis cov amino acids sib xws, thiab ua rau muaj kev poob qis thaum ntxov ntawm ornithine nrog rau ib tug lig augmentation ntawm plasma arginine.
Hauv vivo kawm 3-Methyl-2-oxobutanoic acid (alpha-Ketoisovaleric acid) induces convulsions los ntawm GABAergic thiab glutamatergic mechanisms nyob rau hauv nas.

Product Detail

Khoom cim npe

 

Taw qhia

3-Methyl-2-oxobutyric acid, tseem hu ua tert-butoxypropionic acid, TBAOH, yog cov organic compound.

 

Zoo:

3-Methyl-2-oxobutyric acid yog cov xim tsis muaj xim rau daj daj daj nrog cov ntxhiab tsw. Nws tuaj yeem soluble hauv dej thiab ntau cov kuab tshuaj organic, tab sis insoluble nyob rau hauv non-polar solvents xws li roj av ethers.

 

Siv:

3-Methyl-2-oxobutyric acid feem ntau yog siv los ua alkali catalyst hauv organic synthesis, tshwj xeeb tshaj yog nyob rau hauv kev hloov pauv. Nws tuaj yeem ua rau cov tshuaj tiv thaiv xws li esterification, etherification, amidation, olefin ntxiv, thiab lwm yam. Nws kuj tseem siv tau los ua kua-theem catalyst rau catalyze cov tshuaj tiv thaiv xws li oxidation, hydrogenation, thiab alkydation.

 

Txoj kev:

3-Methyl-2-oxobutyric acid tuaj yeem tau los ntawm reacting propanol nrog sodium tert-butoxide (los yog tert-butanol thiab sodium hydroxide). Cov kauj ruam tshwj xeeb yog react propanol nrog tert-butyl sodium oxide ntawm qhov kub thiab txias, thiab tom qab ntawd cov khoom tau txais los ntawm kev ua kom tsis muaj zog.

 

Cov ntaub ntawv kev nyab xeeb:

3-Methyl-2-oxobutyric acid yog khaus thiab corrosive thiab yuav tsum tau zam los ntawm kev sib cuag nrog daim tawv nqaij, qhov muag, thiab ua pa ib ntsuj av. Cov hnab looj tes tiv thaiv, tsom iav, thiab qhov ncauj qhov ntswg yuav tsum hnav thaum siv. Nyob rau hauv rooj plaub ntawm kev sib cuag, yaug nrog dej kom ntau thiab nrhiav kev kho mob tam sim ntawd. Nws yuav tsum tau muab cia rau hauv qhov chaw txias, qhov cua, kom deb ntawm hluav taws thiab oxidants.


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