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4-Hydroxybenzyl cawv (CAS # 623-05-2) Featured duab
  • 4-Hydroxybenzyl cawv (CAS # 623-05-2) 1

4-Hydroxybenzyl cawv (CAS # 623-05-2)

Chemical Property:

Molecular Formula C7H8O2
Molar Mass 124.14 Nws
Qhov ntom 1.1006 (zeeg)
Melting Point 114-122 ° C (lit.)
Boling Point 251-253 ° C
Flash Point 251-253 ° C
JECFA Number 955 ua
Dej Solubility Soluble hauv dej (6.7 mg / ml ntawm 20 ° C), dioxane (100 mg / ml), 1N NaOH (50 mg / ml), DMSO, thiab methanol.
Solubility Soluble nyob rau hauv methanol, ethanol, DMSO thiab lwm yam organic solvents.
Vapor Siab 0.0104mmHg ntawm 25 ° C
Qhov tshwm sim Paj yeeb, beige (crystalline hmoov)
Xim Paj yeeb rau beige
BRN 1858967 ib
pKa pK1: 9.82 (25 ° C)
Kev cia khoom Khaws hauv qab +30 ° C.
rhiab heev Lub teeb Sensitive/Air Sensitive
Refractive Index 1.5035 (kwv yees)
MDL PAB 00004658
Physical thiab Chemical Properties melting point 110-112 ° C
Siv Siv ua ib qho nruab nrab hauv cov organic synthesis
Kev tshawb nrhiav hauv vitro 4-Hydroxybenzyl cawv inhibits proliferation ntawm eEND2 hlwb thiab suppresses kev tsiv teb tsaws ntawm eEND2 hlwb, nrog rau inhibition ntawm actin filament reorganization. 4-Hydroxybenzyl cawv induces apoptotic tuag ntawm cov qog hlwb.
Hauv vivo kawm 4-Hydroxybenzyl cawv muaj antiangiogenic, anti-inflammatory thiab anti-nociceptive kev ua tau los ntawm nws cov down-regulating kev ua ntawm TSIS MUAJ ntau lawm. 4-Hydroxybenzyl cawv (200 mg / kg) zoo inhibits kev loj hlob thiab angiogenesis ntawm kev tsim cov qog. 4-Hydroxybenzyl cawv ameliorates ischemic raug mob tshwm sim los ntawm lub sij hawm focal cerebral ischemia nyob rau hauv nas, thiab cov nyhuv neuroprotective no tej zaum yuav muaj feem cuam tshuam rau attenuate apoptosis txoj kev.

Product Detail

Khoom cim npe

Hazard Cov Cim Xi-xaj
Risk Codes R36 - Khau qhov muag
R36/37/38 - Kab mob rau qhov muag, ua pa thiab tawv nqaij.
Kev nyab xeeb piav qhia S26 - Thaum sib cuag nrog lub qhov muag, yaug tam sim ntawd nrog dej txaus thiab nrhiav kev kho mob.
S24/25 - Tsis txhob sib cuag nrog daim tawv nqaij thiab qhov muag.
S36 - Hnav khaub ncaws tiv thaiv zoo.
WGK Germany 3
RTECS TIAB SA 4796800
FLUKA BRAND F CODE 8-9-23
HS Code 29072900 ib
Kev Ceeb Toom Irritant/Keep Cold/Air Sensitive/Light Sensitive

 

Taw qhia

Hydroxybenzyl cawv yog cov organic compound nrog cov qauv tshuaj ntawm C6H6O2, feem ntau hu ua phenol methanol. Nov yog qee yam khoom siv, kev siv, kev npaj thiab cov ntaub ntawv kev nyab xeeb txog hydroxybenzyl cawv:

 

Zoo:

Cov tsos mob: tsis muaj xim rau yellowish khoom los yog mucous kua.

Solubility: Soluble nyob rau hauv cov organic solvents xws li dej, cawv thiab ether.

 

Siv:

Preservatives: Nws muaj cov tshuaj tua kab mob thiab tshuaj tua kab mob, thiab hydroxybenzyl cawv kuj tseem siv los ua ntoo khaws cia.

 

Txoj kev:

Hydroxybenzyl cawv feem ntau yog tsim los ntawm cov tshuaj tiv thaiv ntawm para-hydroxybenzaldehyde nrog methanol. Cov tshuaj tiv thaiv tuaj yeem catalyzed los ntawm tus neeg sawv cev oxidizing, xws li catalyst Cu (II.) lossis ferric chloride (III.). Cov tshuaj tiv thaiv feem ntau yog nqa tawm ntawm chav tsev kub.

 

Cov ntaub ntawv kev nyab xeeb:

Hydroxybenzyl cawv muaj cov tshuaj toxicity tsawg, tab sis kev saib xyuas tseem yuav tsum tau ua kom muaj kev nyab xeeb.

Nyob rau hauv rooj plaub ntawm kev sib cuag nrog daim tawv nqaij, yaug tam sim ntawd nrog dej ntau. Yog tias nqos tau, nrhiav kev kho mob sai.

Kev sib cuag nrog oxidants, acids, thiab phenols yuav tsum tau zam thaum tuav thiab khaws cia kom tsis txhob muaj kev phom sij txaus ntshai.

Thaum siv lossis khaws cia, nws yuav tsum khaws cia kom deb ntawm qhov qhib nplaim taws lossis kub kub kom tsis txhob muaj hluav taws kub.

  • Yav dhau los:
  • Tom ntej:
    • Sau koj cov lus ntawm no thiab xa tuaj rau peb

    cov khoom muaj feem xyuam