5-Bromo-2-fluoro-4-methyl-pyridine (CAS # 864830-16-0)
| Risk Codes | R22 - Ua phem yog tias nqos R37/38 - Kab mob ua pa thiab tawv nqaij. R41 - Riam phom loj rau qhov muag |
| Kev nyab xeeb piav qhia | S26 - Thaum sib cuag nrog lub qhov muag, yaug tam sim ntawd nrog dej txaus thiab nrhiav kev kho mob. S39 - Hnav qhov muag / ntsej muag tiv thaiv. |
| Hazard Class | IRRITANT |
Taw qhia
Nws yog ib qho organic compound nrog cov mis molecular C≡H∞BrFN, uas muaj fluorine atom, ib pawg methyl thiab bromine atom hloov ntawm lub nplhaib pyridine.
Xwm:
yog ib yam khoom, tshuaj lom thiab irritating. Nws yog soluble nyob rau hauv cov kuab tshuaj organic xws li ethanol thiab dimethylformamide ntawm chav tsev kub, thiab muaj peev xwm hydrogen daim ntawv cog lus nrog ib co hydrogen daim ntawv cog lus (xws li, cawv).
Siv:
Nws feem ntau yog siv los ua cov khoom pib lossis nruab nrab hauv cov organic synthesis cov tshuaj tiv thaiv. Nws tuaj yeem siv rau hauv kev npaj cov tshuaj, tshuaj tua kab thiab lwm yam organic tebchaw. Nws ntau yam kev siv suav nrog kev tshawb fawb tshuaj, tshuaj synthesis thiab cov ntaub ntawv tshawb fawb.
Txoj Kev Npaj:
Txoj kev npaj ntawm fluorination tuaj yeem ua tiav los ntawm benzyl bromination thiab fluorination. Ua ntej, ib qho benzyl compound (4-methylpyridine) yog reacted nrog benzylidene bromide los tsim bromobenzyl compound (2-bromo-4-methylpyridine). Cov tshuaj no yog tom qab ntawd ua haujlwm nrog hydrofluoric acid los tsim cov khoom siv fluorinated (phosphonium).
Cov ntaub ntawv kev nyab xeeb:
yog tshuaj lom, yuav tsum tau siv cov kev tiv thaiv tsim nyog. Tsis txhob tiv tauj nrog daim tawv nqaij, qhov muag thiab ua pa thaum ua haujlwm. Yuav tsum tau siv rau hauv qhov chaw muaj cua zoo, thiab hnav cov tsom iav tiv thaiv, hnab looj tes thiab qhov ncauj qhov ntswg. Khaws kom deb ntawm hluav taws thiab oxidizing tus neeg sawv cev, thiab tsis txhob muaj cov tshuaj tiv thaiv nrog lwm yam tshuaj. Yog tias kis tau los yog nqus tau, nrhiav kev kho mob tam sim ntawd.
