Alpha-Arbutin CAS Nr .: 84380-01-8
Risk thiab Safety
| WGK Germany | 3 |
Cov ntaub ntawv
| Txheej txheem cej luam | arbutin yog hydroquinone glycoside compound, tshuaj lub npe rau 4-hydroxyphenyl-d-glucopyranoside (y), muaj nyob rau hauv dais txiv hmab txiv ntoo, bilberry thiab lwm yam nroj tsuag, yog ib tug tshiab uas tsis yog khaus, tsis ua xua, ntuj whitening active tshuaj uas muaj zog compatibility. Arbutin muaj ob pawg qauv thiab ua haujlwm ua haujlwm hauv nws cov qauv molecular: ib qho yog cov kua nplaum nplaum; Lwm qhov yog phenolic hydroxyl pawg. Lub cev lub cev ntawm α-arbutin zoo li cov hmoov dawb mus rau lub teeb grey, uas yog ntau soluble hauv dej thiab ethanol. |
| kev ua tau zoo | α-arbutin muaj kev kho mob zoo dua ntawm cov caws pliav los ntawm UV Burns, muaj kev tiv thaiv zoo dua, kho thiab ua kom tawv nqaij. Nws tuaj yeem inhibit qhov tsim thiab tso tawm ntawm melanin, tshem tawm pob thiab freckles. |
| mechanism ntawm kev ua | Lub tshuab ntxuav hniav dawb ntawm α-arbutin ncaj qha inhibits tyrosinase kev ua, yog li txo qis melanin ntau lawm, tsis yog txo melanin ntau lawm los ntawm inhibiting cell loj hlob los yog tyrosinase noob qhia. Raws li α-Arbutin yog ib qho txiaj ntsig zoo dua thiab muaj kev nyab xeeb dua cov khoom siv tshuaj pleev ib ce, ntau lub tuam txhab tshuaj pleev ib ce hauv tsev thiab txawv teb chaws tau txais α-arbutin es tsis txhob ntawm β-arbutin ua ib qho tshuaj dawb. |
| Daim ntawv thov | alpha-Arbutin yog ib yam tshuaj uas zoo ib yam li arbutin, tuaj yeem tiv thaiv kev tsim thiab tso tawm ntawm melanin, tshem tawm pob thiab freckles. Cov txiaj ntsig tau pom tias arbutin tuaj yeem cuam tshuam cov haujlwm ntawm tyrosinase ntawm qhov tsis tshua muaj siab, thiab nws cov nyhuv inhibitory ntawm tyrosinase zoo dua li ntawm arbutin. alpha-arbutin tuaj yeem siv los ua cov tshuaj pleev xim rau hauv cov tshuaj pleev ib ce. |
| purification thiab kev txheeb xyuas | Cov qauv tau txais los ntawm cov tshuaj tiv thaiv yog thawj zaug muab rho tawm nrog ethyl acetate, ces muab rho tawm nrog n-butanol, cov qauv tau sau los ntawm evaporation ntawm lub teb evaporator thiab centrifuged. Lub supernatant tau soj ntsuam los ntawm HPLC thiab muab piv nrog HPLC chromatogram ntawm α-arbutin, seb tus qauv thiab α-arbutin muaj tib lub sij hawm tuav tau muab piv, thiab seb tus qauv muaj α-Arbutin yog qhov ua ntej txiav txim siab. Cov khoom tom qab rho tawm thiab ua kom huv si tau txheeb xyuas los ntawm qhov zoo ion hom ntawm LC-ESI-MS / MS. Los ntawm kev sib piv cov txheeb ze molecular loj ntawm α- dais txiv hmab txiv ntoo nrog cov txheeb ze molecular loj ntawm α-arbutin tus qauv, nws yuav txiav txim seb cov khoom yog α-arbutin. |
| Kev siv | α-arbutin tuaj yeem cuam tshuam tyrosinase kev ua haujlwm ntawm qhov qis qis, nws cov nyhuv inhibitory ntawm tyrosinase zoo dua li ntawm arbutin. |
Sau koj cov lus ntawm no thiab xa tuaj rau peb
