N- (tert-Butoxycarbonyl)-L-aspartic acid (CAS # 13726-67-5)
Risk thiab Safety
| Hazard Cov Cim | Xn – Ua phem |
| Risk Codes | R20/21/22 - Ua phem los ntawm kev nqus pa, tiv thaiv daim tawv nqaij thiab yog tias nqos. R36/37/38 - Kab mob rau qhov muag, ua pa thiab tawv nqaij. |
| Kev nyab xeeb piav qhia | S26 - Thaum sib cuag nrog lub qhov muag, yaug tam sim ntawd nrog dej txaus thiab nrhiav kev kho mob. S36 - Hnav khaub ncaws tiv thaiv zoo. S24/25 - Tsis txhob sib cuag nrog daim tawv nqaij thiab qhov muag. |
| WGK Germany | 3 |
| HS Code | 2924 19 00 Nws |
N-(tert-Butoxycarbonyl)-L-aspartic acid (CAS # 13726-67-5) Taw qhia
Boc-L-aspartic acid yog ib qho organic compound uas feem ntau siv los ua pab pawg tiv thaiv hauv peptide synthesis. Nws cov qauv tshuaj yog C13H19NO6 thiab nws qhov hnyav molecular yog 293.29. Boc sawv cev rau N-tert-butoxycarbonyl.
Boc-L-aspartic acid feem ntau muaj cov khoom nram qab no:
1. Cov tsos: xim tsis muaj xim crystalline hmoov;
2. melting point: txog 152-155 ℃;
3. Solubility: Soluble nyob rau hauv ib co organic solvents, xws li dimethyl sulfoxide thiab dichloromethane, insoluble nyob rau hauv dej;
4. stability: decomposition yuav tshwm sim thaum muaj zog oxidant thiab lub teeb.
Kev siv tseem ceeb ntawm Boc-L-aspartic acid yog ib pab pawg tiv thaiv hauv peptide synthesis. Nws tiv thaiv cov pab pawg amine nyob rau sab saw ntawm L-aspartic acid kom tsis txhob muaj kev cuam tshuam tsis zoo. Thaum lub sij hawm peptide synthesis, Boc-L-aspartic acid reacts nrog lwm cov amino acids los yog peptide ntu los tsim peptide chains tshiab. Tom qab ua tiav cov synthesis, cov pab pawg tiv thaiv yuav raug tshem tawm los ntawm kev kho cov kua qaub kom tau lub hom phiaj peptide lossis cov protein.
Boc-L-aspartic acid feem ntau yog npaj los ntawm cov txheej txheem hluavtaws paub. Luv luv, L-aspartic acid tuaj yeem tsim los ntawm kev ua haujlwm L-aspartic acid nrog t-Boc-L acid thiab dimethylformamide. Cov txheej txheem hluavtaws tshwj xeeb tuaj yeem pom hauv cov ntaub ntawv tshuaj lom neeg.
Hais txog cov ntaub ntawv kev nyab xeeb, koj yuav tsum tau xyuam xim rau cov ntsiab lus hauv qab no:
1. Boc-L-aspartic acid yog ib yam khoom uas muaj toxicity. Kev tiv thaiv tsim nyog yuav tsum tau ua thaum lub sijhawm ua haujlwm, xws li hnav hnab looj tes, tsom iav thiab cov khaub ncaws hauv chav kuaj;
2. tsis txhob nqus cov hmoov los yog tshuaj, tsis txhob sib cuag nrog daim tawv nqaij thiab qhov muag;
3. Thaum siv thiab tuav Boc-L-aspartic acid, nws yuav tsum raug kaw thiab khaws cia kom tsis txhob muaj oxidants thiab lub teeb muaj zog;
4. Thaum cuam tshuam nrog Boc-L-aspartic acid pov tseg, nws yuav tsum muab pov tseg raws li cov cai hauv zos.
Boc-L-aspartic acid feem ntau muaj cov khoom nram qab no:
1. Cov tsos: xim tsis muaj xim crystalline hmoov;
2. melting point: txog 152-155 ℃;
3. Solubility: Soluble nyob rau hauv ib co organic solvents, xws li dimethyl sulfoxide thiab dichloromethane, insoluble nyob rau hauv dej;
4. stability: decomposition yuav tshwm sim thaum muaj zog oxidant thiab lub teeb.
Kev siv tseem ceeb ntawm Boc-L-aspartic acid yog ib pab pawg tiv thaiv hauv peptide synthesis. Nws tiv thaiv cov pab pawg amine nyob rau sab saw ntawm L-aspartic acid kom tsis txhob muaj kev cuam tshuam tsis zoo. Thaum lub sij hawm peptide synthesis, Boc-L-aspartic acid reacts nrog lwm cov amino acids los yog peptide ntu los tsim peptide chains tshiab. Tom qab ua tiav cov synthesis, cov pab pawg tiv thaiv yuav raug tshem tawm los ntawm kev kho cov kua qaub kom tau lub hom phiaj peptide lossis cov protein.
Boc-L-aspartic acid feem ntau yog npaj los ntawm cov txheej txheem hluavtaws paub. Luv luv, L-aspartic acid tuaj yeem tsim los ntawm kev ua haujlwm L-aspartic acid nrog t-Boc-L acid thiab dimethylformamide. Cov txheej txheem hluavtaws tshwj xeeb tuaj yeem pom hauv cov ntaub ntawv tshuaj lom neeg.
Hais txog cov ntaub ntawv kev nyab xeeb, koj yuav tsum tau xyuam xim rau cov ntsiab lus hauv qab no:
1. Boc-L-aspartic acid yog ib yam khoom uas muaj toxicity. Kev tiv thaiv tsim nyog yuav tsum tau ua thaum lub sijhawm ua haujlwm, xws li hnav hnab looj tes, tsom iav thiab cov khaub ncaws hauv chav kuaj;
2. tsis txhob nqus cov hmoov los yog tshuaj, tsis txhob sib cuag nrog daim tawv nqaij thiab qhov muag;
3. Thaum siv thiab tuav Boc-L-aspartic acid, nws yuav tsum raug kaw thiab khaws cia kom tsis txhob muaj oxidants thiab lub teeb muaj zog;
4. Thaum cuam tshuam nrog Boc-L-aspartic acid pov tseg, nws yuav tsum muab pov tseg raws li cov cai hauv zos.
Sau koj cov lus ntawm no thiab xa tuaj rau peb
