BOC-GLY-GLY-GLY-OH (CAS # 28320-73-2)
Taw qhia
Tert-Butoxycarbonylglycyl glycylglycine (Boc-Gly-Gly-Gly-OH) yog cov organic compound nrog cov khoom hauv qab no:
Xwm:
-Qhov tshwm sim: feem ntau yog dawb crystalline hmoov los yog crystalline hmoov
Cov mis mos molecular: C17H30N4O7
Molecular Luj: 402.44g / mol
- Melting point: txog 130-132 ° C
-Solubility: Soluble nyob rau hauv organic solvents xws li dimethylformamide (DMF), dichloromethane, chloroform, thiab lwm yam., insoluble nyob rau hauv dej.
Siv:
Boc-Gly-Gly-Gly-OH feem ntau yog siv hauv cov organic synthesis, feem ntau yog tiv thaiv pab pawg lossis pab pawg. Nws tuaj yeem siv los ua cov pab pawg tiv thaiv ntawm cov amino acids los tiv thaiv cov tshuaj tiv thaiv uas tsis yog tshwj xeeb, thiab feem ntau yog siv rau hauv cov txheej txheem synthesis, peptide synthesis thiab tshuaj synthesis.
Txoj kev:
Ib txoj hauv kev los npaj Boc-Gly-Gly-Gly-OH yog los qhia txog tert-butoxycarbonyl tiv thaiv pab pawg ntawm carboxyl pawg ntawm glycine. Cov kauj ruam tshwj xeeb muaj xws li:
1. Glycine yog reacted nrog ib tug sib tov ntawm sodium nitrite thiab sulfuric acid kom tau tert-butoxycarbonyl glycinate.
2. Cov pab pawg tiv thaiv Ester raug tshem tawm los ntawm cov tshuaj tiv thaiv hydrolysis kom tau txais Boc-glycine.
3. Rov ua cov kauj ruam saum toj no ob zaug los qhia txog pawg carboxyl ntawm glycine rau hauv ob pawg tert-butoxycarbonyl tiv thaiv raws li tau txais Boc-Gly-Gly-Gly-OH.
Cov ntaub ntawv kev nyab xeeb:
Kev siv Boc-Gly-Gly-Gly-OH yuav tsum xyuam xim rau cov teeb meem kev nyab xeeb hauv qab no:
-Tsis txhob sib cuag nrog daim tawv nqaij thiab qhov muag, vim nws yuav ua rau tawv nqaij thiab qhov muag.
- Hnav cov hnab looj tes tiv thaiv tsim nyog, tsom iav thiab khaub ncaws tiv thaiv thaum ua haujlwm.
- Ua haujlwm nyob rau hauv qhov chaw uas muaj cua zoo kom tsis txhob nqus nws cov plua plav lossis vapor.
-yuav tsum khaws cia kom deb ntawm qhov hluav taws kub, cua sov thiab oxidant, khaws lub thawv ntim, khaws cia rau hauv qhov chaw txias, qhuav.
