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Tom ntej: Boc-L-Glutamic Acid 1-benzyl ester (CAS # 30924-93-7)

Chemical Property:

Molecular Formula C17H23 NPO 6
Molar Mass 337.37 ib
Qhov ntom 1?+-.0.06 g/cm3 (Tswj)
Melting Point 95.0 txog 99.0 ° C
Boling Point 522.6 ± 50.0 ° C (Tshaj tawm)
Solubility Chloroform (me ntsis), Methanol (me ntsis)
Qhov tshwm sim Khoom
Xim Dawb
BRN 2482076 ib
pKa 4.48 ± 0.10 (Tshaj tawm)
Kev cia khoom Muab ntim rau hauv qhuav, Khaws rau hauv lub freezer, hauv qab -20 ° C
Refractive Index -30 ° (C = 0.7, MeOH)
MDL TIAB SA 00065568
Siv Boc-Glu-OBzl yog N-terminal tiv thaiv amino acid siv nyob rau hauv cov khoom theem polypeptide synthesis (SPPS) kom cov peptide nkaus xwb muaj benzyl glutamate residues.

Product Detail

Khoom cim npe

Kev nyab xeeb piav qhia 24/25 - Tsis txhob sib cuag nrog daim tawv nqaij thiab qhov muag.
WGK Germany 3
HS Code 29242990 ib

 

Taw qhia

Boc-L-Glutamic acid 1-benzyl ester (Boc-L-Glutamic acid 1-benzyl ester) yog cov organic compound nrog cov tshuaj formula C17H19NO6 thiab cov txheeb ze molecular loj ntawm 337.34. Nws yog cov khoom dawb, soluble hauv cov kuab tshuaj organic xws li ethanol, dimethylformamide thiab chloroform.

 

Boc-L-Glutamic acid 1-benzyl ester feem ntau yog siv rau hauv cov synthesis ntawm peptide tebchaw. Nws tuaj yeem siv los ua tus neeg sawv cev micellar lossis pab pawg tiv thaiv los tiv thaiv cov amino acid pab pawg kom tsis txhob muaj kev xav tsis zoo ntawm cov tshuaj tiv thaiv, thiab tib lub sijhawm tuaj yeem txhim kho cov txiaj ntsig. Tsis tas li ntawd, nws kuj tuaj yeem siv rau kev sib txuas ntawm cov tshuaj polypeptide thiab cov tshuaj bioactive molecules.

 

Txoj kev npaj Boc-L-Glutamic acid 1-benzyl ester feem ntau yog los qhia Boc tiv thaiv pawg rau hauv cov amino pawg ntawm glutamic acid, thiab ua esterification cov tshuaj tiv thaiv nrog benzyl anhydride ester ntawm txoj haujlwm no. Cov tshuaj tiv thaiv feem ntau yog ua raws li qhov nruab nrab lossis theem pib thiab feem ntau yuav tsum muaj qee lub sijhawm los xyuas kom tiav cov tshuaj tiv thaiv. Cov khoom tau txais tuaj yeem ua kom huv los ntawm crystallization lossis ntxiv purification cov kauj ruam.

 

Hais txog cov ntaub ntawv kev nyab xeeb, kev nyab xeeb tshwj xeeb ntawm Boc-L-Glutamic acid 1-benzyl ester yuav tsum tau tshawb fawb ntxiv thiab kev ntsuam xyuas. Txawm li cas los xij, raws li tus neeg sawv cev tshuaj, nws yuav muaj qee yam khaus thiab toxicity. Cov txheej txheem kuaj xyuas tsim nyog yuav tsum tau ua raws li kev sib cuag lossis siv, thiab yuav tsum tau ceev faj txog kev nyab xeeb tsim nyog, suav nrog kev hnav cov khoom tiv thaiv tus kheej (xws li, hnab looj tes, hnab looj tes, tsom iav, thiab lwm yam). Thaum siv lossis pov tseg, pov tseg yuav tsum muab pov tseg kom zoo kom tsis txhob muaj kuab paug ib puag ncig.


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