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Tom ntej: Boc-L-glutamic acid 1-tert-butyl ester (CAS # 24277-39-2)

Chemical Property:

Molecular Formula C14H25NO6
Molar Mass 303.35 Nws
Qhov ntom 1.121 ± 0.06 g / cm3 (Kev kwv yees)
Melting Point 111.0 txog 115.0 ° C
Boling Point 449.8 ± 40.0 ° C (Predicted)
Flash Point 225.8°C dej
Solubility Soluble nyob rau hauv dimethyl formamide.
Vapor Siab 2.42E-09mmHg ntawm 25 ° C
Qhov tshwm sim Crystalline hmoov
Xim Dawb mus Yuav luag dawb
BRN 3653769 ib
pKa 4.48 ± 0.10 (Tshaj tawm)
Kev cia khoom Muab ntim rau hauv qhuav, Khaws rau hauv lub freezer, hauv qab -20 ° C
Refractive Index 1.47 ib
MDL TIAB SA 00038273

Product Detail

Khoom cim npe

Risk Codes R22/22 -
R36/37/38 - Kab mob rau qhov muag, ua pa thiab tawv nqaij.
Kev nyab xeeb piav qhia S4 - Cia kom deb ntawm lub tsev nyob.
S7 - Khaws lub thawv kaw kom nruj.
S28 - Tom qab sib cuag nrog daim tawv nqaij, ntxuav tam sim nrog xab npum-suds ntau.
S35 - Cov khoom no thiab nws lub thawv yuav tsum muab pov tseg rau hauv txoj kev nyab xeeb.
S44 -
WGK Germany 3
HS Code 2924 19 00 Nws

 

Taw qhia

NT-boc-L-glutamic acid A- T-butyl-ester (NT-boc-L-glutamic acid A- T-butyl-ester) yog cov organic compound. Nws cov qauv tshuaj yog C15H25NO6 thiab nws qhov hnyav molecular yog 315.36g / mol.

 

Xwm:

NT-boc-L-glutamic acid A-T-butyl-ester yog cov khoom siv lead ua, soluble hauv cov kuab tshuaj organic xws li methanol, ethanol thiab methylene chloride, insoluble hauv dej. Nws tuaj yeem tsim ib qho siv lead ua ib leeg, cov qauv uas feem ntau txiav txim siab los ntawm X-ray crystallography. Lub compound yog ruaj khov ntawm chav tsev kub.

 

Siv:

NT-boc-L-glutamic acid A- T-butyl-ester feem ntau yog siv los ua A tiv thaiv pawg hauv cov organic synthesis. Nws tuaj yeem tiv thaiv pawg carboxyl (COOH) ntawm glutamic acid los tiv thaiv kev tsis zoo sab hauv cov tshuaj tiv thaiv. Cov pab pawg tiv thaiv tuaj yeem raug tshem tawm yooj yim los ntawm txoj kev tsim nyog thaum tsim nyog kom tau txais cov thawj glutamic acid compound.

 

Txoj kev:

Cov txheej txheem ntawm kev npaj NT-boc-L-glutamic acid A- T-butyl-ester feem ntau yog nqa tawm los ntawm cov tshuaj lom neeg cov tshuaj lom neeg. Ua ntej, nyob rau hauv kev tiv thaiv ntawm nitrogen, tert-butoxycarbonyl-L-glutamic acid yog reacted nrog tert-butyl magnesium bromide los tsim ib qho nruab nrab; Tom qab ntawd, nws yog reacted nrog sodium bicarbonate los tsim cov khoom kawg, uas yog, NT-boc-L-glutamic acid A- T-butyl-ester.

 

Cov ntaub ntawv kev nyab xeeb:

NT-boc-L-glutamic acid A- T-butyl-ester feem ntau muaj kev nyab xeeb nyob rau hauv kev ua haujlwm tshuaj lom neeg ua haujlwm. Txawm li cas los xij, vim tias nws yog cov khoom siv organic, nws tseem yuav tsum tau siv cov cuab yeej tiv thaiv tus kheej tsim nyog hauv cov chaw kuaj tshuaj, xws li cov hnab looj tes, tsom iav thiab cov khaub ncaws tiv thaiv. Tsis tas li ntawd, cov txheej txheem kuaj kev nyab xeeb yuav tsum tau ua raws.


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