BOC-L-Phenylglycine (CAS # 2900-27-8)
| Kev nyab xeeb piav qhia | S22 - Tsis txhob nqus plua plav. S24/25 - Tsis txhob sib cuag nrog daim tawv nqaij thiab qhov muag. |
| WGK Germany | 3 |
| HS Code | 29242970 ib |
Taw qhia
N-Boc-L-Phenylglycine yog ib qho organic compound uas yog tsim los ntawm kev tsim cov tshuaj lom neeg ntawm cov amino pawg (NH2) ntawm glycine thiab carboxyl pawg (COOH) ntawm benzoic acid. Nws cov qauv muaj cov pab pawg tiv thaiv (Boc pab pawg), uas yog tert-butoxycarbonyl pawg, uas yog siv los tiv thaiv cov reactivity ntawm cov amino pawg.
N-Boc-L-phenylglycine muaj cov khoom nram qab no:
- Cov tsos: Dawb crystalline khoom
- Solubility: Soluble nyob rau hauv qee cov organic solvents, xws li dimethylformamide (DMF), dichloromethane, thiab lwm yam
N-Boc-L-phenylglycine feem ntau yog siv nyob rau hauv ntau kauj ruam cov tshuaj tiv thaiv nyob rau hauv cov organic synthesis, tshwj xeeb tshaj yog rau synthesis ntawm peptide tebchaw. Cov pab pawg tiv thaiv Boc tuaj yeem tiv thaiv los ntawm cov kab mob acidic, kom cov amino pawg tuaj yeem ua rau muaj kev cuam tshuam thiab tom qab ntawd ua cov tshuaj tiv thaiv tom ntej. N-Boc-L-phenylglycine kuj tseem siv tau los ua cov khoom siv rau kev tsim kho cov chaw chiral hauv peptide synthesis.
Kev npaj ntawm N-Boc-L-phenylglycine yog ua los ntawm cov kauj ruam hauv qab no:
Glycine yog esterified nrog benzoic acid kom tau benzoic acid-glycinate ester.
Siv lithium borotrimethyl ether (LiTMP) cov tshuaj tiv thaiv, benzoic acid-glycinate ester yog protonated thiab reacted nrog Boc-Cl (tert-butoxycarbonyl chloride) kom tau N-Boc-L-phenylglycine.
- N-Boc-L-phenylglycine tej zaum yuav ua rau khaus ntawm lub qhov muag, tawv nqaij, thiab ua pa thiab yuav tsum zam thaum siv.
- Cov khoom siv tiv thaiv tus kheej xws li cov hnab looj tes kuaj, tsom iav kev nyab xeeb, thiab lwm yam yuav tsum tau hnav thaum ua haujlwm.
- Nws yuav tsum tau ua nyob rau hauv ib tug zoo-ventilated kuaj ib puag ncig.
- Tsis txhob sib cuag nrog oxidants thiab muaj zog acids thaum khaws cia.
- Yog tias nqos los yog nqus tau, nrhiav kev kho mob tam sim ntawd, nqa lub thawv ntawm cov khoom sib xyaw, thiab muab cov ntaub ntawv kev nyab xeeb tsim nyog rau tus kws kho mob.
