Cbz-L-Glutamic acid 1-benzyl ester (CAS # 3705-42-8)
Taw qhia
Z-Glu-OBzl (Z-Glu-OBzl) yog cov organic compound feem ntau siv los tiv thaiv pab pawg amino acids. Cov hauv qab no yog cov lus piav qhia ntawm cov khoom, kev siv, kev npaj thiab kev nyab xeeb cov ntaub ntawv ntawm lub compound:
Xwm:
Cov mis mos molecular: C17H17NO4
Molecular Luj: 303.32g / mol
-Zoo: Dawb crystalline hmoov
Melting Point: 84-85 ° C
-Solubility: Soluble nyob rau hauv cov organic solvents xws li dimethyl sulfoxide thiab dimethylformamide
- Cbz tiv thaiv pab pawg tuaj yeem raug tshem tawm los ntawm palladium hydride catalyst nyob rau hauv acidic mob
Siv:
- Z-Glu-OBzl yog ib pawg tiv thaiv glutamic acid (Glu), uas tuaj yeem siv rau hauv kev sib txuas ntawm amino acid derivatives, polypeptides thiab cov proteins.
-Raws li pab pawg tiv thaiv rau cov amino acids hauv cov khoom siv hluavtaws, nws tuaj yeem tiv thaiv cov amine pawg ntawm glutamic acid, tiv thaiv nws los ntawm kev cuam tshuam los ntawm cov tshuaj tsis haum, thiab pab tshem tawm thaum xav tau.
Txoj Kev Npaj:
-Kev npaj ntawm Z-Glu-OBzl feem ntau suav nrog cov txheej txheem ntau kauj ruam thiab koom nrog cov tshuaj tiv thaiv kab mob. Ib txoj hauv kev zoo tshaj plaws yog thawj zaug tiv thaiv pawg carboxyl ntawm glutamic acid li t-butoxycarbonyl ester (Boc) thiab tom qab ntawd tiv thaiv cov amino pawg li Cbz. Thaum kawg, cov khoom xav tau Z-Glu-OBzl yog tsim los ntawm cov tshuaj tiv thaiv nrog benzyl chloroformate.
Cov ntaub ntawv kev nyab xeeb:
- Z-Glu-OBzl yuav tsum tau kho raws li cov tshuaj tiv thaiv kab mob thiab tsis txhob cuam tshuam ncaj qha rau ntawm daim tawv nqaij thiab qhov muag.
-Thaum siv hauv chav kuaj, yuav tsum ua raws li cov txheej txheem kev nyab xeeb kom raug, suav nrog kev hnav tsom iav tiv thaiv, hnab looj tes thiab cov tsho hauv chav kuaj.
-Kev nqus los yog nqus ntawm cov khoom sib xyaw yuav tsum tau zam thiab kev tiv thaiv hluav taws thiab tawg yuav tsum tau ua thaum khaws cia.
-Lub compound yuav tsum muab tso rau hauv ib qho chaw zoo-ventilated thaum lub sij hawm ua, thiab pov tseg yuav tsum tau muab pov tseg kom zoo raws li cov kev cai hauv zos.
