D-2-Amino-3-phenylpropionic acid (CAS # 673-06-3)
| Risk Codes | 34 – Ua rau kub hnyiab |
| Kev nyab xeeb piav qhia | S24/25 - Tsis txhob sib cuag nrog daim tawv nqaij thiab qhov muag. S45 - Thaum muaj xwm txheej lossis yog tias koj tsis xis nyob, nrhiav kev kho mob tam sim ntawd (qhia daim ntawv lo thaum twg ua tau.) S36/37/39 - Hnav cov khaub ncaws tiv thaiv tsim nyog, hnab looj tes thiab tiv thaiv qhov muag / ntsej muag. S27 - Tshem tawm tag nrho cov khaub ncaws tsis huv tam sim ntawd. S26 - Thaum sib cuag nrog lub qhov muag, yaug tam sim ntawd nrog dej txaus thiab nrhiav kev kho mob. |
| WGK Germany | 3 |
| RTECS | UA 7533000 |
| TSCA | Yog lawm |
| HS Code | 29224995 ib |
| Kev Ceeb Toom | Irritant |
| Toxicity | TDLO orl-hmn: 500 mg/kg/5W-I: GIT JACTDZ 1(3), 124,82 |
Taw qhia
D-phenylalanine yog cov khoom siv protein ntau nrog cov tshuaj npe D-phenylalanine. Nws yog tsim los ntawm D-configuration ntawm phenylalanine, ib tug natural amino acid. D-phenylalanine zoo ib yam li phenylalanine, tab sis nws muaj cov haujlwm lom neeg sib txawv.
Nws tuaj yeem siv los ua cov khoom siv raw hauv cov tshuaj, cov khoom noj qab haus huv thiab cov khoom noj khoom haus los txhim kho kev ua haujlwm ntawm lub paj hlwb thiab tswj cov tshuaj sib npaug hauv lub cev. Nws kuj yog siv rau hauv kev sib txuas ntawm cov tshuaj nrog cov tshuaj tua kab mob thiab cov tshuaj tua kab mob.
Kev npaj ntawm D-phenylalanine tuaj yeem ua tau los ntawm kev siv tshuaj lom neeg lossis biotransformation. Cov txheej txheem tshuaj synthesis feem ntau siv cov tshuaj tiv thaiv enantioselective kom tau txais cov khoom nrog D configurations. Txoj kev biotransformation siv cov catalytic nkaus ntawm cov kab mob lossis cov enzymes los hloov cov phenylalanine rau hauv D-phenylalanine.
Nws yog ib qho tsis ruaj tsis khov uas muaj qhov cuam tshuam rau degradation los ntawm tshav kub thiab lub teeb. Kev noj ntau dhau yuav ua rau mob plab hnyuv. Nyob rau hauv tus txheej txheem ntawm kev siv D-phenylalanine, cov koob tshuaj yuav tsum tau tswj nruj me ntsis, thiab cov txheej txheem kev nyab xeeb yuav tsum tau ua raws. Rau cov tib neeg uas tsis haum rau D-phenylalanine lossis muaj cov metabolism hauv phenylalanine txawv txav, nws yuav tsum raug zam lossis siv raws li kev qhia ntawm kws kho mob.
