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D-Glutamine (CAS # 5959-95-5) Featured duab
  • D-Glutamine (CAS # 5959-95-5) 1

D-Glutamine CAS # 5959-95-5

Chemical Property:

Molecular Formula C5 H10 N2 O3
Molar Mass 146.14 Nws
Qhov ntom 1.3394 (zeeg)
Melting Point 184-185 ° C
Boling Point 265.74 ° C (kwv yees kwv yees)
Kev sib hloov tshwj xeeb (α) -32 º (589nm, c = 10, N HCl)
Dej Solubility 42.53g / L (kub tsis tau teev)
Solubility Soluble hauv dej (9 mg / ml ntawm 25 ° C), DMSO (<1 mg / ml ntawm 25 ° C), thiab ethanol (<1 mg / m)
Qhov tshwm sim Dawb crystalline hmoov
Xim Dawb
BRN 1723796 ib
pKa 2.27 ± 0.10 (Tshaj tawm)
Kev cia khoom Khaws nyob rau hauv qhov chaw tsaus, inert cua, chav tsev kub
Refractive Index -33 ° C = 5,5 mol / LH
MDL TIAB SA 00065607
Physical thiab Chemical Properties Melting Point: 185
Kev tshawb nrhiav hauv vitro Glutamine yog ib qho tseem ceeb amino acid nyob rau hauv lub hauv paus paj hlwb (CNS), ua lub luag haujlwm tseem ceeb hauv glutamate / GABA-Glutamine voj voog (GGC). Nyob rau hauv GGC, Glutamine yog kis los ntawm astrocytes mus rau neurons, qhov uas nws yuav ntxiv cov inhibitory thiab excitatory neurotransmitter pas dej ua ke. D-Glutamine tau siv los kawm txog nws lub luag haujlwm hauv kev sib tham txog kev tiv thaiv acetaldehyde-vim cuam tshuam kev cuam tshuam ntawm kev ua haujlwm hauv Caco-2 cell monolayer. Lub luag haujlwm ntawm L-Glutamine hauv kev tiv thaiv plab hnyuv epithelium los ntawm acetaldehyde-vim cuam tshuam kev cuam tshuam ntawm kev cuam tshuam kev ua haujlwm raug soj ntsuam hauv Caco-2 cell monolayer. L-Glutamine txo cov acetaldehyde-vim txo qis hauv transepithelilal hluav taws xob tiv thaiv thiab nce permeability rau inulin thiab lipopolysaccharide nyob rau hauv ib lub sij hawm- thiab koob tshuaj-nyob ntawm seb; D-Glutamine, L-aspargine, L-arginine, L-lysine, lossis L-alanine ua tsis muaj kev tiv thaiv tseem ceeb. D-Glutamine kuj tsis cuam tshuam rau acetaldehyde-vim txo qis hauv TER thiab nce inulin flux. D-Glutamine lossis glutaminase inhibitor los ntawm lawv tus kheej tsis cuam tshuam TER lossis inulin flux hauv kev tswj lossis acetaldehyde-kho cell monolayers. Tsis muaj kev cuam tshuam ntawm D-Glutamine hauv kev tiv thaiv los ntawm acetaldehyde qhia tias L-Glutamine-mediated tiv thaiv yog stereospecific.

Product Detail

Khoom cim npe

Hazard Cov Cim Xi-xaj
Risk Codes 36/37/38 – Khaus qhov muag, ua pa thiab tawv nqaij.
Kev nyab xeeb piav qhia S36/37/39 - Hnav cov khaub ncaws tiv thaiv tsim nyog, hnab looj tes thiab tiv thaiv qhov muag / ntsej muag.
S26 - Thaum sib cuag nrog lub qhov muag, yaug tam sim ntawd nrog dej txaus thiab nrhiav kev kho mob.
S27 - Tshem tawm tag nrho cov khaub ncaws tsis huv tam sim ntawd.
S24/25 - Tsis txhob sib cuag nrog daim tawv nqaij thiab qhov muag.
WGK Germany 3
HS Code 29241900 ib

 

Taw qhia

Lub unnatural isomer ntawm glutamine yog insoluble nyob rau hauv methanol, ethanol, ether thiab benzene.

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