Ethyl 3-(4-(methylamino)-3-nitro-N-(pyridin-2-yl)benzamido)propanoate (CAS # 429659-01-8)
Taw qhia
Ethyl 3-(4-(methylamino)-3-nitro-N-(pyridin-2-yl)benzoylamido)propionate, tseem hu ua MTT (Meta-Toluidine ortho-Toluenesulphonic acid triazine ester), yog ib yam tshuaj. Nws muaj cov khoom nram qab no:
Qhov tsos: Dawb khov
Solubility: Soluble hauv cawv, ketones thiab chloroform
Cov kev siv tseem ceeb ntawm MTT yog raws li hauv qab no:
Kev tshawb fawb txog kev lom neeg: MTT tau siv dav los txiav txim siab ntawm cell proliferation thiab cell viability. Nws hloov MTT mus rau hauv cov khoom xiav uas yaj hauv cov hlwb los ntawm kev txo nws, uas tuaj yeem siv los txiav txim siab txog cell viability.
Feem ntau, txoj kev npaj ntawm MTT tuaj yeem ua tau los ntawm cov kauj ruam hauv qab no:
Methylaniline reacted nrog 2-nitrobenzoyl chloride kom tau 3-(4-methylaminobenzoyl) benzoyl chloride.
Cov khoom tau txais nyob rau hauv kauj ruam 1 yog reacted nrog 2-pyridone los tsim 3-(4-methylaminobenzoylamido) benzoyl chloride.
Cov khoom tau txais nyob rau hauv kauj ruam 2 yog reacted nrog ethyl 3-aminopropionate los tsim ethyl 3-(4-methylaminobenzoylamido) propionate.
Cov khoom kawg, MTT, yog purified los ntawm crystallization los yog lwm txoj kev.
Cov Ntaub Ntawv Kev Nyab Xeeb: MTT yog cov tshuaj lom, thiab yuav tsum tau saib xyuas kom siv thiab pov tseg kom raug. Cov cuab yeej tiv thaiv tsim nyog xws li hnab looj tes, tsom iav, thiab chav kuaj txheej yuav tsum tau hnav thaum ua haujlwm. Tsis txhob nqus pa, tiv thaiv daim tawv nqaij, thiab noj. Thaum siv lossis pov tseg cov khoom pov tseg, ua raws li cov txheej txheem kev nyab xeeb muaj feem xyuam, thiab muab pov tseg tam sim ntawd thiab ntxuav txhua qhov tsis pom kev. Nyob rau hauv rooj plaub ntawm kev nqus los yog kev sib cuag ntawm daim tawv nqaij, nrhiav kev kho mob tam sim ntawd.