Fmoc-D-Cyclohexyl glycine (CAS # 198543-96-3)
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Fmoc-D-Cyclohexyl glycine (CAS # 198543-96-3) Cov ntaub ntawv
| Siv | Fluorene methoxycarbonyl D-cyclohexylglycine yog ib qho tshuaj thiab tshuaj nruab nrab, fluorenyl chloride (FMOC-Cl) yog chloroformate. Nws yog siv los tsim fluorene methoxycarbonyl (FMOC pab pawg) rau hauv fluorene methoxycarbonyl carbamate FMOC carbamate, uas yog ib hom amino tiv thaiv pawg. |
| Kev npaj | Cov synthesis ntawm fluorene methoxycarbonyl D-cyclohexylglycine tau tshaj tawm nyob rau hauv cov ntaub ntawv. Siv cyclohexyl bromide ua raw cov ntaub ntawv, nyob rau hauv lub xub ntiag ntawm sodium alkoxide, nws undergoes ib tug alkylation cov tshuaj tiv thaiv nrog diethyl malonate, thiab ces hydrolyzes, acidifies, thiab decarboxylates kom tau cyclohexyl acetic acid; tom qab ntawd ces brominated thiab ammonolysis DL-Cyclohexylglycine; Thaum kawg, acylation cov tshuaj tiv thaiv tshwm sim nyob rau hauv lub xub ntiag ntawm fluorene methoxycarbonyl chloride kom tau fluorene methoxycarbonyl D-cyclohexylglycine [1]. Cov txheej txheem synthesis yog raws li nram no: |
Yav dhau los: AC-TYR-NH2 (CAS # 1948-71-6) Tom ntej: 2-Amino-4-bromobenzoic acid (CAS # 20776-50-5)
