FMOC-Glycine CAS Nr 29022-11-5

Taw qhia

N-Fmoc-glycine yog ib qho tseem ceeb amino acid derivative, thiab nws cov tshuaj npe yog N-(9H-fluoroeidone-2-oxo)-glycine. Cov hauv qab no yog kev qhia txog cov khoom, kev siv, kev npaj thiab cov ntaub ntawv kev nyab xeeb ntawm N-Fmoc-glycine:

Zoo:

- Cov tsos: dawb los yog dawb dawb

- Solubility: Soluble nyob rau hauv cov organic solvents xws li dimethyl sulfoxide (DMSO) thiab methylene chloride, me ntsis soluble nyob rau hauv cawv, yuav luag insoluble nyob rau hauv dej.

Siv:

N-Fmoc-glycine feem ntau yog siv rau peptide synthesis hauv solid-phase synthesis (SPPS). Raws li kev tiv thaiv amino acid, nws tau ntxiv rau cov saw hlau polypeptide los ntawm cov khoom siv-theem synthesis, thiab thaum kawg lub hom phiaj peptide tau txais los ntawm cov tshuaj tiv thaiv ntawm pab pawg deprotecting.

Txoj kev:

Kev npaj ntawm N-Fmoc-glycine feem ntau yog ua los ntawm cov tshuaj tiv thaiv. Glycine reacted nrog N-fluorophenyl methyl cawv thiab lub hauv paus (xws li, triethylamine) los tsim N-fluorophenylmethyl-glycine hydrochloride. Tom qab ntawd, hydrochloric acid raug tshem tawm los ntawm qee yam deacidifier, xws li dimethyl sulfoxide lossis sec-butanol, muab N-Fmoc-glycine.

Cov ntaub ntawv kev nyab xeeb:

N-Fmoc-Glycine muaj kev nyab xeeb nyob rau hauv ib txwm ua haujlwm

- Thov hnav cov khoom tiv thaiv tus kheej tsim nyog xws li cov hnab looj tes kuaj thiab tiv thaiv qhov muag.

- Tsis txhob nqus los yog tiv nrog daim tawv nqaij thiab qhov muag.

- Ua raws li tag nrho cov cai tswj kev nyab xeeb thiab cov txheej txheem kuaj thaum khaws cia thiab tuav.

- Ua tib zoo saib xyuas qhov sib xyaw ntawm qhov hluav taws xob thiab hluav taws xob zoo li qub thaum lub sij hawm tuav cov txheej txheem los tiv thaiv kev pheej hmoo ntawm hluav taws thiab tawg.

- Kev pov tseg cov khoom pov tseg kom raug raws li kev cia thiab pov tseg ntawm cov khoom.