Tom ntej: Fmoc-L-2-Aminobutyric Acid (CAS # 135112-27-5)
Risk thiab Safety
Kev nyab xeeb piav qhia | S22 - Tsis txhob nqus plua plav. S24/25 - Tsis txhob sib cuag nrog daim tawv nqaij thiab qhov muag. |
WGK Germany | 3 |
HS Code | 29242970 ib |
Hazard Class | IRRITANT |
Fmoc-L-2-Aminobutyric acid (CAS # 135112-27-5) Taw qhia
L-2-(fluorenylmethoxycarbonylamino) butyric acid, tseem hu ua Fmoc-glutamic acid (L-2-(9-fluorenylmethoxycarbonylamino) butyric acid), yog cov organic. Cov hauv qab no yog cov lus piav qhia ntawm qee yam ntawm nws cov khoom, kev siv, txoj kev thiab cov ntaub ntawv kev nyab xeeb:
Xwm:
-Tshuaj: tsis muaj xim lossis daj me ntsis crystalline hmoov;
Cov mis mos molecular: C26H23NO4;
Molecular hnyav: 413.47g / mol;
- melting point: txog 166-168 ℃;
-Solubility: Fmoc-glutamic acid yog soluble nyob rau hauv cov organic solvents xws li dimethylformamide thiab hydrofluoric acid.
Siv:
Fmoc-glutamic acid, raws li ib tug tiv thaiv pab pawg neeg compound, feem ntau yog siv nyob rau hauv peptide synthesis, tshwj xeeb tshaj yog nyob rau hauv synthesis ntawm ruaj khov peptide sequences thiab cov synthesis ntawm Levenstein peptides (Levenshtein peptide). Nws tuaj yeem siv los ua cov khoom sib txuas nruab nrab ntawm cov amino acids, lossis siv rau hauv cov txheej txheem synthesis, kev ua haujlwm siab ua kua chromatography, thiab lwm yam.
Txoj Kev Npaj:
Kev npaj ntawm Fmoc-glutamic acid feem ntau suav nrog cov kauj ruam hauv qab no:
1. Hauv lub cev tsis muaj dej, L-glutamic acid yog reacted nrog Fmoc-OSu (fluorenylmethoxycarbonyl-chloro anhydride), thiab sodium chloride (NaCl) yog siv los txhawb cov tshuaj tiv thaiv los tsim Fmoc-glutamic acid Fmoc-A ntsev.
2. Rau Fmoc-glutamic acid ntsev, nws yog yaj nyob rau hauv ib tug hnyav (xws li dimethylformamide) thiab raug rau ib tug tsim nyog purification txoj kev (xws li crystallization) kom tau Fmoc-glutamic acid.
Cov ntaub ntawv kev nyab xeeb:
Fmoc-glutamic acid feem ntau kuj ruaj khov thiab tsis muaj tshuaj lom nyob rau hauv kev ua haujlwm niaj hnub. Tab sis raws li cov organic compound, tseem yuav tsum tau ua tib zoo saib xyuas cov kev ntsuas kev nyab xeeb hauv qab no:
-Tsis txhob nqus cov plua plav, tiv thaiv daim tawv nqaij thiab qhov muag;
- Thaum lub sijhawm ua haujlwm, hnav cov hnab looj tes tiv thaiv, tsom iav thiab cov khaub ncaws tiv thaiv uas ua tau raws li kev nyab xeeb;
- Ua haujlwm nyob rau hauv ib qho chaw zoo-ventilated kom tsis txhob raug ncaj qha mus ntev;
-Yog tias cov khib nyiab pov tseg los ntawm qhov sib xyaw no yuav tsum muab pov tseg, nws yuav tsum muab pov tseg kom raug raws li cov cai hauv zos.
Xwm:
-Tshuaj: tsis muaj xim lossis daj me ntsis crystalline hmoov;
Cov mis mos molecular: C26H23NO4;
Molecular hnyav: 413.47g / mol;
- melting point: txog 166-168 ℃;
-Solubility: Fmoc-glutamic acid yog soluble nyob rau hauv cov organic solvents xws li dimethylformamide thiab hydrofluoric acid.
Siv:
Fmoc-glutamic acid, raws li ib tug tiv thaiv pab pawg neeg compound, feem ntau yog siv nyob rau hauv peptide synthesis, tshwj xeeb tshaj yog nyob rau hauv synthesis ntawm ruaj khov peptide sequences thiab cov synthesis ntawm Levenstein peptides (Levenshtein peptide). Nws tuaj yeem siv los ua cov khoom sib txuas nruab nrab ntawm cov amino acids, lossis siv rau hauv cov txheej txheem synthesis, kev ua haujlwm siab ua kua chromatography, thiab lwm yam.
Txoj Kev Npaj:
Kev npaj ntawm Fmoc-glutamic acid feem ntau suav nrog cov kauj ruam hauv qab no:
1. Hauv lub cev tsis muaj dej, L-glutamic acid yog reacted nrog Fmoc-OSu (fluorenylmethoxycarbonyl-chloro anhydride), thiab sodium chloride (NaCl) yog siv los txhawb cov tshuaj tiv thaiv los tsim Fmoc-glutamic acid Fmoc-A ntsev.
2. Rau Fmoc-glutamic acid ntsev, nws yog yaj nyob rau hauv ib tug hnyav (xws li dimethylformamide) thiab raug rau ib tug tsim nyog purification txoj kev (xws li crystallization) kom tau Fmoc-glutamic acid.
Cov ntaub ntawv kev nyab xeeb:
Fmoc-glutamic acid feem ntau kuj ruaj khov thiab tsis muaj tshuaj lom nyob rau hauv kev ua haujlwm niaj hnub. Tab sis raws li cov organic compound, tseem yuav tsum tau ua tib zoo saib xyuas cov kev ntsuas kev nyab xeeb hauv qab no:
-Tsis txhob nqus cov plua plav, tiv thaiv daim tawv nqaij thiab qhov muag;
- Thaum lub sijhawm ua haujlwm, hnav cov hnab looj tes tiv thaiv, tsom iav thiab cov khaub ncaws tiv thaiv uas ua tau raws li kev nyab xeeb;
- Ua haujlwm nyob rau hauv ib qho chaw zoo-ventilated kom tsis txhob raug ncaj qha mus ntev;
-Yog tias cov khib nyiab pov tseg los ntawm qhov sib xyaw no yuav tsum muab pov tseg, nws yuav tsum muab pov tseg kom raug raws li cov cai hauv zos.
Sau koj cov lus ntawm no thiab xa tuaj rau peb