Tom ntej: Fmoc-L-Aspartic acid-1-benzyl ester (CAS # 86060-83-5)

Taw qhia

Fmoc-Asp-OBzl (Fmoc-Asp-OBzl) yog ib qho khoom siv feem ntau siv hauv peptide synthesis thiab cov khoom theem synthesis.

Xwm:

Fmoc-Asp-OBzl yog dawb crystalline khoom nrog zoo solubility thiab stability. Nws cov qauv tshuaj yog C33H29NO7 thiab nws qhov hnyav molecular yog 555.6. Nws muaj fluorenyl tiv thaiv pab pawg (Fmoc) thiab benzoyl tiv thaiv pawg (Bzl) los tiv thaiv aspartic acid.

Siv:

Fmoc-Asp-OBzl ua cov pab pawg tiv thaiv tuaj yeem siv rau hauv kev sib txuas ntawm peptides thiab cov proteins. Nws tuaj yeem siv rau cov txheej txheem kev sib xyaw ua ke thiab kev tiv thaiv pab pawg tshem tawm cov kauj ruam hauv peptide synthesis cov tshuaj tiv thaiv. Hauv kev sib xyaw ua ke, cov aspartic acid residue tuaj yeem Fmoc-Asp-OBzl tiv thaiv nyob rau hauv qhov tshwm sim peptide fragment los tiv thaiv qhov tsis xav tau.

Txoj Kev Npaj:

Kev npaj ntawm Fmoc-Asp-OBzl feem ntau ua tiav los ntawm cov tshuaj synthesis. Tshwj xeeb, Fmoc-Asp-OBzl tuaj yeem tau txais los ntawm kev ua haujlwm fluorenecyl chloride (Fmoc-Cl) nrog aspartic acid -1-benzyl ester (Asp-OBzl).

Cov ntaub ntawv kev nyab xeeb:

Fmoc-Asp-OBzl yog ib qho tshuaj uas yuav tsum tau ua hauv chav kuaj. Ua raws li cov txheej txheem kev nyab xeeb hauv chav kuaj thaum tuav, xws li hnav cov cuab yeej tiv thaiv tsim nyog (xws li hnab looj tes, tsom iav, thiab cov tsho hauv chav kuaj) kom tsis txhob sib cuag nrog daim tawv nqaij, qhov muag, thiab ua pa. Tsis tas li ntawd, nws yuav tsum tau muab cia rau hauv qhov chaw qhuav, txias, thiab deb ntawm cov hluav taws kub thiab cov khoom siv hluav taws xob. Thaum siv Fmoc-Asp-OBzl, kev saib xyuas yuav tsum tau them rau nws cov toxicity thiab irritation, thiab xyuas kom meej tias nws ua haujlwm nyob rau hauv ib qho chaw nyab xeeb.