Fmoc-L-glutamic acid-gamma-benzyl ester (CAS # 123639-61-2)
Fluorene methoxycarbonyl-L-glutamic acid-Γ-benzyl yog cov organic compound siv nyob rau hauv peptide synthesis nyob rau hauv solid-phase synthesis. Nws qhov xwm txheej:
- Cov tsos mob: Dawb rau daj ntseg daj
- Solubility: Fmoc-L-Glu (OtBu)-OH muaj solubility zoo ntawm cov organic solvents.
Kev siv tseem ceeb ntawm Fmoc-L-Glu (OtBu)-OH yog raws li pab pawg tiv thaiv hauv peptide synthesis. Thaum tsim cov peptide chains, Fmoc-L-Glu (OtBu)-OH khi rau cov amino acids, tiv thaiv lawv cov kev ua ub no tiv thaiv tsis muaj kev cuam tshuam nrog lwm cov reactants. Tom qab cov tshuaj tiv thaiv tiav, Fmoc-L-Glu (OtBu)-OH tuaj yeem raug tshem tawm los ntawm kev tshem tawm cov pab pawg tiv thaiv kom rov ua haujlwm ntawm cov amino acids.
Kev npaj ntawm Fmoc-L-Glu (OtBu)-OH yog qhov nyuaj thiab feem ntau yuav tsum tau siv cov txheej txheem ntawm cov organic synthesis. Glutamic acid yog reacted nrog bromoacetate kom tau ethyl glutamate. Tom qab ntawd, ethyl glutamate reacted nrog benzyl cawv los tsim ethyl glutamate benzyl cawv ester. Ethyl glutamate benzyl cawv ester tau hnov mob nrog Fmoc-Cl los tsim cov khoom lag luam Fmoc-L-Glu (OtBu)-OH.
Cov Ntaub Ntawv Kev Nyab Xeeb: Fmoc-L-Glu (OtBu)-OH yog cov tshuaj hauv chaw kuaj mob thiab yuav tsum tau siv nyob rau hauv kev ua haujlwm nyab xeeb. Ua raws li kev soj ntsuam kev nyab xeeb, suav nrog kev hnav cov cuab yeej tiv thaiv tus kheej (xws li, hnab looj tes, hnab looj tes, thiab lwm yam), zam kev sib chwv ntawm daim tawv nqaij thiab nqus pa, thiab ua haujlwm hauv qhov chaw ua pa kom zoo. Cov tshuaj yuav tsum tau muab cia rau hauv ib lub thawv airtight, kom deb ntawm ignition thiab oxidants.