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Tom ntej: Fmoc-O-tert-butyl-L-tyrosine (CAS # 71989-38-3)

Chemical Property:

Molecular Formula C28H29NO5
Molar Mass 459.53 ib
Qhov ntom 1.218 ± 0.06 g / cm3 (Kev kwv yees)
Melting Point 150 ° C (txog)
Boling Point 658.2 ± 55.0 ° C (Tshaj tawm)
Kev sib hloov tshwj xeeb (α) -28 º (c=1, DMF)
Flash Point 351.9°C dej
Solubility Chloroform (me ntsis), DMF (me ntsis), Methanol (me ntsis)
Vapor Siab 3.2E-18mmHg ntawm 25 ° C
Qhov tshwm sim Dawb siv lead ua
Xim Dawb
BRN 42165 2
pKa 2.97 ± 0.10 (Kev kwv yees)
Kev cia khoom Khaws hauv qab +30 ° C.
Refractive Index -30 ° (C = 1, DMF)
MDL PAB 00037129
Physical thiab Chemical Properties Dawb crystalline hmoov; Insoluble hauv dej thiab roj av ether, soluble hauv ethyl acetate, methanol thiab DMF; mp yog 150-151 ℃; Kev sib hloov kho qhov muag tshwj xeeb [α]20D 10 5.2 ° (0.5-2.0 mg / ml, ethyl acetate), [α]20D-27.6 ° (0.5-2.0 mg / ml, DMF), [α] 20D-6 ° (0.5- 2.0 mg/ml, methanol).

Product Detail

Khoom cim npe

Hazard Cov Cim Xi-xaj
Risk Codes 36/37/38 – Khaus qhov muag, ua pa thiab tawv nqaij.
Kev nyab xeeb piav qhia S26 - Thaum sib cuag nrog lub qhov muag, yaug tam sim ntawd nrog dej txaus thiab nrhiav kev kho mob.
S24/25 - Tsis txhob sib cuag nrog daim tawv nqaij thiab qhov muag.
WGK Germany 3
HS Code 29242970 ib

 

Taw qhia

Fluorene methoxycarbonyl-oxotert-butyl-tyrosine yog cov tshuaj lom neeg feem ntau hu ua FMOC-Tyr(tBu)-OH. Cov hauv qab no yog cov lus qhia txog nws qhov xwm txheej, kev siv, kev npaj thiab kev nyab xeeb cov ntaub ntawv:

 

Zoo:

- Cov tsos: dawb los yog dawb dawb.

- Solubility: Soluble nyob rau hauv qee cov organic solvents, xws li dimethyl sulfoxide thiab dimethylformamide.

 

Siv:

- Tiv thaiv pab pawg hauv cov tshuaj synthesis: FMOC pawg tuaj yeem siv los tiv thaiv cov amino pawg hauv phenolic tebchaw los tiv thaiv lawv los ntawm kev ua haujlwm. FMOC-Tyr(tBu)-OH tuaj yeem siv los ua cov khoom pib rau kev npaj peptide chains hauv tshuaj synthesis.

 

Txoj kev:

Txoj kev npaj ntawm FMOC-Tyr(tBu)-OH tuaj yeem ua tiav los ntawm cov kauj ruam hauv qab no:

- Fluorenyl chloride (FMOC-Cl) yog reacted nrog tert-butyl (tBu-NH2) muab fluorenylmethoxycarbonyl-tert-butichsyl (FMOC-tBu-NH-).

- Tom qab ntawd, hnov ​​​​qhov tshwm sim FMOC-tBu-NH- nrog tyrosine (Tyr-OH) los tsim FMOC-Tyr(tBu)-OH.

 

Cov ntaub ntawv kev nyab xeeb:

- Kev siv FMOC-Tyr (tBu)-OH yog ua raws li cov txheej txheem kuaj kev nyab xeeb.

- Tsis txhob kov cov tawv nqaij thiab qhov muag, thiab hnav hnab looj tes tiv thaiv thiab tsom iav thaum siv.

- Siv nyob rau hauv qhov chaw uas muaj cua zoo, nyob deb ntawm hluav taws thiab combustibles.

- Nws yuav tsum tsis txhob muab tso rau hauv ib puag ncig thiab yuav tsum tau tuav thiab pov tseg raws li cov cai hauv zos.

 


  • Yav dhau los:
  • Tom ntej:

  • Sau koj cov lus ntawm no thiab xa tuaj rau peb