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khoom

CAS Nr 17902-23-7

Chemical Property:

Molecular Formula C8H9FN2O3
Molar Mass 200.17 Nws
Qhov ntom 1.3222 (kwv yees)
Melting Point 171-173 ° C (lit.)
Solubility DMSO:> 50mg/mL
Qhov tshwm sim Dawb crystalline hmoov
Xim dawb mus dawb
Merck 14, 9112 ib
pKa 7.63 ± 0.10 (Kev kwv yees)
Kev cia khoom chav kub
Refractive Index 1.557 ib
MDL TIAB SA 00012351
Physical thiab Chemical Properties Melting point 168-171 ° C
Siv Fluorouracil derivatives, nrog rau kev tiv thaiv mob qog noj ntshav

Product Detail

Khoom cim npe

Hazard Cov Cim T – Toxic
Risk Codes 23/24/25 – Toxic los ntawm inhalation, nyob rau hauv kev sib cuag nrog daim tawv nqaij thiab yog hais tias nqos.
Kev nyab xeeb piav qhia S22 - Tsis txhob nqus plua plav.
S36/37/39 - Hnav cov khaub ncaws tiv thaiv tsim nyog, hnab looj tes thiab tiv thaiv qhov muag / ntsej muag.
S45 - Thaum muaj xwm txheej lossis yog tias koj tsis xis nyob, nrhiav kev kho mob tam sim ntawd (qhia daim ntawv lo thaum twg ua tau.)
UN IDs UN 2811 6.1/PG 2
WGK Germany 3
RTECS YR0450000
HS Code 293499 0
Hazard Class 6.1
Packing Group II
Toxicity LD50 hauv nas (mg / kg): 900 qhov ncauj (3 hnub) (Yasumoto); 750 ip (FR 1574684), kuj tau tshaj tawm tias 1150 ip (Smart)

 

Taw qhia

Trifluoromethylation yog ib qho tshuaj lom neeg cov tshuaj tiv thaiv nyob rau hauv uas cov pab pawg trifluoromethyl tuaj yeem nkag mus rau hauv cov organic molecules siv tegafluor reagents xws li TMSCF3.

 

Cov khoom ntawm tesafluor:

- Tegafluor yog ib pawg tseem ceeb ntawm kev hloov pauv cov tshuaj tiv thaiv, uas tuaj yeem qhia cov pab pawg trifluoromethyl nrog qee yam electron ceev los hloov cov khoom ntawm lub cev thiab tshuaj lom neeg ntawm molecules.

- Trifluoromethyl pawg muaj zog electron attraction, uas yuav ua rau kom lub electrophilicity ntawm lub molecule thiab solubility ntawm cov kuab tshuaj.

- Cov khoom ntawm cov tshuaj tiv thaiv tegafluor feem ntau yog tshuaj lom neeg ruaj khov thiab ua haujlwm lom.

 

Kev siv ntawm tesafluor:

- Hauv kev tshawb fawb ntawm cov ntaub ntawv tshawb fawb, tegafluor tuaj yeem hloov pauv cov khoom saum npoo ntawm cov ntaub ntawv, ua kom lawv ruaj khov thiab tiv taus huab cua.

 

Txoj kev npaj ntawm tegafluor:

- Feem ntau siv tegafluor reagents suav nrog: TMSCF3, Ruppert-Prakash reagent, thiab lwm yam.

- Cov tshuaj tiv thaiv Tegafluor feem ntau yog ua nyob rau hauv qhov chaw tsis muaj zog, siv cov kuab tshuaj inert (xws li, methylene chloride, chloroform) ua cov tshuaj tiv thaiv nruab nrab.

- Cov kev mob tshwm sim feem ntau xav tau cov tshuaj tiv thaiv kub thiab cov tshuaj tiv thaiv ntev dua, thiab feem ntau yuav tsum tau ntxiv cov catalyst (piv txwv li, tooj liab catalyst).

 

Cov ntaub ntawv kev nyab xeeb ntawm tegafur:

- Tegafluor reagents yog tshuaj lom thiab corrosive, thiab yuav tsum tau ceev faj kom tsim nyog thaum tuav.

- Cov pa roj (xws li hydrogen fluoride) uas tsim tawm thaum lub sij hawm cov tshuaj tiv thaiv kuj tseem txaus ntshai thiab yuav tsum tau ua haujlwm nyob rau hauv qhov cua zoo.

- Kev saib xyuas yuav tsum tau ua kom tsis txhob muaj kev sib cuag nrog dej lossis av noo thaum lub sijhawm ua haujlwm kom tsis txhob muaj tshuaj lom neeg tsis zoo.

- Cov tshuaj tiv thaiv thiab cov khoom lag luam nyob rau hauv cov tshuaj tiv thaiv tegafluor yuav tsum tau kho kom raug thiab pov tseg pov tseg.


  • Yav dhau los:
  • Tom ntej:

  • Sau koj cov lus ntawm no thiab xa tuaj rau peb