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khoom

L-Pyroglutamic acid CAS 98-79-3

Chemical Property:

Molecular Formula C5H7NO3
Molar Mass 129.11 Nws
Qhov ntom 1.3816 (kev kwv yees kwv yees)
Melting Point 160-163 ° C (lit.)
Boling Point 239.15 ° C (kwv yees kwv yees)
Kev sib hloov tshwj xeeb (α) -27.5 º (c=10, 1 N NaOH)
Flash Point 227.8°C dej
Dej Solubility 10-15 g / 100 mL (20 ºC) yog '
Solubility Soluble nyob rau hauv dej, cawv, acetone thiab glacial acetic acid, me ntsis soluble nyob rau hauv ethyl acetate, insoluble nyob rau hauv ether.
Vapor Siab 0.002Pa ntawm 25 ℃
Qhov tshwm sim Dawb zoo siv lead ua
Xim Dawb mus rau dawb
Merck 14,800 1
BRN 82132 ib
pKa 3.32 (ntawm 25 ℃)
PH 1.7 (50g / l, H2O, 20 ℃)
Kev cia khoom 2-8 ° C
Kev ruaj ntseg ruaj khov. Incompatible nrog cov hauv paus, acids, muaj zog oxidizing tus neeg sawv cev.
Refractive Index -10 ° C = 5, H2O

Product Detail

Khoom cim npe

Risk thiab Safety

Hazard Cov Cim Xi-xaj
Risk Codes 36/37/38 - Ua rau khaus qhov muag, ua pa thiab tawv nqaij.
Kev nyab xeeb piav qhia S26 - Thaum sib cuag nrog lub qhov muag, yaug tam sim ntawd nrog dej txaus thiab nrhiav kev kho mob.
S36 - Hnav khaub ncaws tiv thaiv zoo.
S37/39 - Hnav cov hnab looj tes tsim nyog thiab tiv thaiv qhov muag / ntsej muag
WGK Germany 3
RTECS TW 3710 000
FLUKA BRAND F CODE 21
TSCA Yog lawm
HS Code 29337900 ib
Hazard Class IRRITANT

Kev siv

Kev siv

Qhia ntxiv
1. [IF=1.902] Zhi Rao et al."Multicomponent kev txiav txim siab ntawm tsoos suav tshuaj npaj yin-zhi-huang inje…

Cov ntaub ntawv yooj yim

oxidized proline tseem hu uaL-pyroglutamic acid. kwv tij molecular mass 129.12. Lub melting point yog 162-163 ° C. Tsis txhob yaj hauv ether, ethyl acetate-soluble, soluble hauv dej (25 ° C 40), ethanol, acetone thiab acetic acid. Kev sib hloov kho qhov muag tshwj xeeb -11.9 ° (c = 2,H2O). Nws cov ntsev ntsev tuaj yeem siv los ua cov khoom siv moisturizing nyob rau hauv cov tshuaj pleev ib ce, nws cov nyhuv moisturizing zoo dua glycerol, sorbitol, tsis muaj tshuaj lom, tsis muaj stimulating nyhuv, rau kev tu tawv nqaij thiab kho cov plaub hau tshuaj pleev ib ce; Cov khoom no muaj cov nyhuv inhibitory ntawm tyrosine oxidase, tuaj yeem tiv thaiv kev tso tawm ntawm melanin zoo li, muaj cov nyhuv whitening ntawm daim tawv nqaij; Nws muaj cov nyhuv softening ntawm daim tawv nqaij, tuaj yeem siv rau cov tshuaj pleev ib ce; Kuj tseem siv tau ua surfactant rau detergents; Tshuaj reagents, rau kev daws teeb meem ntawm racemic amines; Organic intermediates.

 

Taw qhia pyroglutamic acid yog 5-oxyproline. Nws yog tsim los ntawm lub cev qhuav dej ntawm α-NH2 pawg thiab γ-hydroxyl pawg ntawm glutamic acid los tsim ib daim ntawv cog lus molecular lactam; Nws kuj tuaj yeem tsim los ntawm kev poob ib pawg Amido hauv glutamine molecule. Yog tias glutathione synthetase tsis txaus, tuaj yeem ua rau pyroglutamemia, cov tsos mob tshwm sim. Pyroglutamemia yog ib qho teeb meem ntawm cov organic acid metabolism los ntawm glutathione synthetase deficiency. Kev kho mob tshwm sim ntawm kev yug me nyuam 12 ~ 24 teev ntawm qhov pib, nce hemolysis, jaundice, mob metabolic Acidosis, mob hlwb, thiab lwm yam .; Cov zis muaj pyroglutamic acid, lactic acid, Alpha deoxy4 glycoloacetic acid lipid. Kev kho mob, cov tsos mob, xyuam xim kho cov khoom noj tom qab hnub nyoog.
khoom L-pyroglutamic acid, tseem hu ua L-pyroglutamic acid, L-pyroglutamic acid. Los ntawm ethanol thiab roj av ether sib tov nyob rau hauv cov nag lossis daus ntawm cov xim tsis muaj xim orthorhombic ob lub khob hliav qab Crystal, melting point ntawm 162 ~ 163 ℃. Soluble hauv dej, cawv, acetone thiab acetic acid, ethyl acetate-soluble, insoluble hauv ether. Kev sib hloov kho qhov muag tshwj xeeb -11.9 ° (c = 2,H2O).

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