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Levodopa (CAS # 59-92-7) Featured duab
  • Levodopa (CAS # 59-92-7) 1

Levodopa CAS Nr .: 59-92-7

Chemical Property:

Molecular Formula C9H11 NPO 4
Molar Mass 197.19 Nws
Qhov ntom 1.3075 (zeeg)
Melting Point 276-278 ° C (lit.)
Boling Point 334.28 ° C (kwv yees kwv yees)
Kev sib hloov tshwj xeeb (α) -11.7 º (c = 5.3, 1N HCl)
Flash Point 225 ° C
Dej Solubility Me ntsis soluble hauv dej, dilute hydrochloric acid thiab formic acid. Insoluble hauv ethanol.
Solubility Yooj yim soluble hauv dilute hydrochloric acid thiab formic acid, soluble hauv dej, insoluble hauv ethanol, benzene, chloroform thiab ethyl acetate
Vapor Siab 7.97E-09mmHg ntawm 25 ° C
Qhov tshwm sim Dawb mus rau milky dawb crystalline hmoov
Xim Dawb rau creamy
Merck 14,5464 ib
BRN 2215169 ib
pKa 2.32 (ntawm 25 ℃)
Kev cia khoom 2-8 ° C
Kev ruaj ntseg ruaj khov. Incompatible nrog muaj zog oxidizing neeg sawv cev. Lub teeb thiab huab cua rhiab heev.
rhiab heev Sensitive rau lub teeb thiab huab cua
Refractive Index -12 ° C = 5, 1 mol / LH
MDL PAB 00002598
Physical thiab Chemical Properties melting point 295 ° C
kev sib hloov kho qhov muag -11.7 ° (c = 5.3, 1N HCl)
Siv Ib qho tshuaj zoo rau kev kho mob tuag tes tuag taw ntawm kev poob siab, feem ntau yog siv rau Parkinson's syndrome, thiab lwm yam

Product Detail

Khoom cim npe

Hazard Cov Cim Xn – Ua phem
Risk Codes R22 - Ua phem yog tias nqos
R36/37/38 - Kab mob rau qhov muag, ua pa thiab tawv nqaij.
R20/21/22 - Ua phem los ntawm kev nqus pa, tiv thaiv daim tawv nqaij thiab yog tias nqos.
Kev nyab xeeb piav qhia S26 - Thaum sib cuag nrog lub qhov muag, yaug tam sim ntawd nrog dej txaus thiab nrhiav kev kho mob.
S36 - Hnav khaub ncaws tiv thaiv zoo.
S24/25 - Tsis txhob sib cuag nrog daim tawv nqaij thiab qhov muag.
WGK Germany 3
RTECS YOG 5600000
FLUKA BRAND F CODE 10-23
TSCA Yog lawm
HS Code 29225090 ib
Toxicity LD50 hauv nas (mg / kg): 3650 ± 327 qhov ncauj, 1140 ± 66 ip, 450 ± 42 iv, > 400 sc; Hauv txiv neej, poj niam nas (mg / kg):> 3000,> 3000 qhov ncauj; 624, 663 ib; > 1500, > 1500 sc (Clark)

 

Taw qhia

Pharmacological teebmeem: tshuaj tiv thaiv tremor paralysis. Nws nkag mus rau hauv lub hlwb cov ntaub so ntswg los ntawm cov ntshav-hlwb barrier, thiab decarboxylated los ntawm dopa decarboxylase thiab hloov mus rau hauv dopamine, uas plays lub luag hauj lwm. Nws yog siv rau thawj tremor paralysis thiab non-drug-induced tremor paralysis syndrome. Nws muaj txiaj ntsig zoo rau cov neeg laus laus laus, mob hnyav lossis mob hnyav.

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