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N-Boc-N'-(2-chlorobenzyloxycarbonyl)-L-lysine (CAS # 54613-99-9)

Chemical Property:

Molecular Formula C19H27ClN2O6
Molar Mass 414.88 ib
Qhov ntom 1.236 ± 0.06 g / cm3 (Tshaj tawm)
Melting Point 70-73 ° C
Boling Point 608.3 ± 55.0 ° C (Tshaj tawm)
Flash Point 321.7°C dej
Vapor Siab 1.19E-15mmHg ntawm 25 ° C
Qhov tshwm sim Crystallization
Xim Dawb mus rau dawb
pKa 3.99 ± 0.21 (Tshaj tawm)
Kev cia khoom Muab ntim rau hauv qhuav, 2-8 ° C
Refractive Index 1.531 ib
MDL PAB 00038386
Physical thiab Chemical Properties N-tert-butoxycarbonyl-N'-(2-chlorobenzyloxycarbonyl)-L-lysine yog dawb mus rau-dawb hmoov nyob rau hauv tsos; melting point 70-73 ° C; Qhov ceev 1.236g / cm3.
Siv Kev tiv thaiv lysine yog tshwj xeeb tshaj yog haum rau solid-phase peptide synthesis; 2-CZ kev tiv thaiv yog kwv yees li 50 lub sij hawm ruaj khov dua Z-pab pawg tiv thaiv.

Product Detail

Khoom cim npe

Hazard Cov Cim Xi-xaj
Risk Codes 36/37/38 – Khaus qhov muag, ua pa thiab tawv nqaij.
Kev nyab xeeb piav qhia S26 - Thaum sib cuag nrog lub qhov muag, yaug tam sim ntawd nrog dej txaus thiab nrhiav kev kho mob.
S36 - Hnav khaub ncaws tiv thaiv zoo.
S24/25 - Tsis txhob sib cuag nrog daim tawv nqaij thiab qhov muag.
WGK Germany 3
HS Code 29242990 ib

 

Taw qhia

N-tert-butoxycarbonyl-N'-(2-chlorobenzyloxycarbonyl)-L-lysine yog cov organic compound, feem ntau hu ua CBZ-L-lysine. Cov hauv qab no yog qhov xwm txheej, kev siv, kev npaj thiab cov ntaub ntawv kev nyab xeeb ntawm cov khoom sib xyaw:

 

Zoo:

CBZ-L-lysine yog cov xim tsis muaj xim crystalline nrog cov ntxhiab tsw tshwj xeeb. Nws muaj solubility zoo thiab yog soluble hauv cov organic solvents xws li methanol, chloroform, thiab dimethyl sulfoxide.

 

Siv:

CBZ-L-lysine feem ntau yog siv los ua ib qho ntawm cov amino tiv thaiv pawg hauv cov organic synthesis los tiv thaiv cov amino functional pawg uas nkag siab zoo rau ib puag ncig. Hauv kev sib xyaw ntawm peptide tebchaw, CBZ-L-lysine tuaj yeem siv los tiv thaiv cov amino pawg ntawm lysine txhawm rau tiv thaiv lossis tswj nws cov reactivity hauv cov tshuaj tiv thaiv tshwj xeeb.

 

Txoj kev:

Kev npaj ntawm CBZ-L-lysine feem ntau yog ua los ntawm cov kauj ruam hauv qab no: L-lysine reacted nrog carbon dioxide kom tau txais cov carbonate sib thooj; Tom qab ntawd, cov carbonate yog reacted nrog tert-butoxycarbonyl magnesium chloride kom tau acetyl-tiv thaiv lysine; Tom qab ntawd nws yog reacted nrog 2-chlorobenzyl iodine chloride thiab alkali kom tau CBZ-L-lysine.

 

Cov ntaub ntawv kev nyab xeeb:

Kev siv CBZ-L-lysine yuav tsum tau nrog cov kev ceev faj txog kev nyab xeeb hauv qab no: nws yuav ua rau khaus ntawm qhov muag, tawv nqaij thiab ua pa, thiab kev sib cuag ncaj qha yuav tsum zam thaum ua haujlwm. Cov cuab yeej tiv thaiv tsim nyog xws li tshuaj tiv thaiv tsom iav thiab hnab looj tes yuav tsum hnav thaum siv. Nws yuav tsum tau ua nyob rau hauv ib qho chaw zoo-ventilated kom tsis txhob nqus pa los ntawm lub compound. Yog tias muaj xwm txheej tshwm sim, qhov chaw cuam tshuam yuav tsum tau muab yaug tam sim nrog dej txaus thiab yuav tsum nrhiav kev pab kho mob.


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