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khoom

N-Boc-trans-4-Hydroxy-L-proline methyl ester (CAS # 74844-91-0)

Chemical Property:

Molecular Formula C11H19NO5
Molar Mass 245.27 Nws
Qhov ntom 1.216 ± 0.06 g / cm3 (Kev kwv yees)
Melting Point 92-96 ° C (lit.)
Boling Point 132 ° C / 0.05mmHg (lit.)
Kev sib hloov tshwj xeeb (α) -65 º (c = 1 CHCl3)
Flash Point 156.55°C dej
Solubility Soluble nyob rau hauv chloroform, dichloromethane thiab ethyl acetate.
Vapor Siab 0 mmHg ntawm 25 ° C
Qhov tshwm sim Crystal
Xim Dawb rau lub teeb beige
pKa 14.27 ± 0.40 (Tshaj tawm)
Kev cia khoom Khaws nyob rau hauv qhov chaw tsaus, kaw hauv qhuav, Chav Kub
Refractive Index 1.501 Nws
MDL TIAB SA 00076981

Product Detail

Khoom cim npe

Hazard Cov Cim Xn – Ua phem
Risk Codes R20/21/22 - Ua phem los ntawm kev nqus pa, tiv thaiv daim tawv nqaij thiab yog tias nqos.
R36/37/38 - Kab mob rau qhov muag, ua pa thiab tawv nqaij.
Kev nyab xeeb piav qhia S24/25 - Tsis txhob sib cuag nrog daim tawv nqaij thiab qhov muag.
S36 - Hnav khaub ncaws tiv thaiv zoo.
S26 - Thaum sib cuag nrog lub qhov muag, yaug tam sim ntawd nrog dej txaus thiab nrhiav kev kho mob.
WGK Germany 3
HS Code 29339900 ib
Hazard Class IRRITANT

 

Taw qhia

N-BOC-trans-4-hydroxy-L-proline methyl ester, tag nrho lub npe N-tert-butoxycarbonyl-trans-4-hydroxy-L-proline methyl ester, yog cov organic compound.

 

Zoo:

N-BOC-trans-4-hydroxy-L-proline methyl ester yog dawb crystalline khoom.

 

Siv:

N-BOC-trans-4-hydroxy-L-proline methyl ester feem ntau yog siv los ua cov amino acid tiv thaiv pawg hauv cov organic synthesis chemistry. Nws tuaj yeem siv los ua cov pab pawg tiv thaiv zoo los tiv thaiv cov pab pawg hydroxyl hauv cov amino acids kom tsis txhob muaj kev cuam tshuam tsis zoo hauv kev sib txuas.

 

Txoj kev:

Kev npaj ntawm N-BOC-trans-4-hydroxy-L-proline methyl ester feem ntau yog tau los ntawm reacting N-BOC-4-hydroxy-L-proline nrog methanol. N-BOC-4-hydroxy-L-proline yog reacted nrog ib tug activator (xws li DCC los yog DIC) los tsim ib tug activated ester, thiab ces methanol yog ntxiv rau react nrog nws los tsim N-BOC-trans-4-hydroxy- L-proline methyl ester. Lub hom phiaj cov khoom yog tau los ntawm crystallization los yog lwm yam kev sib cais thiab purification txoj kev.

 

Cov ntaub ntawv kev nyab xeeb: Thaum nws los txog rau cov tshuaj synthesis, kev siv cov cuab yeej thiab cov kev sim yuav tsum muaj kev sib raug zoo. Hauv kev ua haujlwm hauv chaw kuaj mob, yuav tsum tau saib xyuas kom tsis txhob muaj kev sib cuag ncaj qha rau ntawm daim tawv nqaij thiab qhov muag, thiab ua kom muaj cua zoo. Yog tias koj muaj kev tsis xis nyob hauv lub cev lossis lwm yam kev mob tshwm sim, koj yuav tsum nrhiav kev kho mob tam sim ntawd.


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