N-Cbz-D-Tryptophan (CAS # 2279-15-4)

Taw qhia

N(^a)-Benzyloxycarbonyl-D-tryptophan(N(^a)-Benzyloxycarbonyl-D-tryptophan) yog cov tshuaj, tseem hu ua CBZ-D-Trp. Cov hauv qab no yog cov lus piav qhia ntawm nws qhov xwm txheej, kev siv, kev tsim thiab cov ntaub ntawv kev nyab xeeb:

Xwm:

N(^a)-Benzyloxycarbonyl-D-tryptophan yog dawb mus rau yellowish crystalline khoom. Nws yog qhov ruaj khov ntawm chav tsev kub thiab tuaj yeem khaws cia rau lub sijhawm ntev hauv cov dej tsis muaj dej. Nws yog insoluble nyob rau hauv dej, tab sis soluble nyob rau hauv ib co organic solvents xws li methanol thiab dimethyl sulfoxide.

Siv:

N(^a)-Benzyloxycarbonyl-D-tryptophan feem ntau yog siv los tiv thaiv pawg hauv cov organic synthesis, tshwj xeeb tshaj yog nyob rau hauv tshuaj peptide synthesis. Nws lub ntsiab siv yog raws li ib tug derivative ntawm amino acids rau lub synthesis ntawm tshwj xeeb modules nyob rau hauv polypeptide los yog protein chains. Nws tuaj yeem ua lub luag haujlwm tseem ceeb hauv kev sib txuas ntawm cov tshuaj tshiab hauv txoj kev no.

Txoj kev:

Kev npaj ntawm N(^a)-Benzyloxycarbonyl-D-tryptophan feem ntau yog ua los ntawm cov tshuaj synthesis. Ua ntej, benzyl cawv thiab carbon dioxide yog reacted los tsim benzyloxycarboxylic acid, thiab ces cov amino acid tryptophan thiab benzyloxycarboxylic acid yog esterified kom tau CBZ-D-Trp khoom. Cov tshuaj tiv thaiv xav tau kev pab ntawm qee cov organic catalysts thiab cov kuab tshuaj.

Cov ntaub ntawv kev nyab xeeb:

N(^a)-Benzyloxycarbonyl-D-tryptophan muaj qee cov ntaub ntawv kev nyab xeeb, tab sis raws li cov ntaub ntawv muaj, nws feem ntau suav tias yog tshuaj lom. Kev raug mus ntev lossis raug ntau dhau tuaj yeem ua rau muaj teebmeem kev noj qab haus huv. Yog li, kev ntsuas kev nyab xeeb tsim nyog yuav tsum tau ua thaum siv, khaws cia thiab tuav cov khoom sib xyaw no, suav nrog hnav cov khoom tiv thaiv tus kheej tsim nyog thiab tuav hauv qhov chaw muaj cua zoo. Nyob rau tib lub sijhawm, nws yuav tsum ua raws li cov txheej txheem kev nyab xeeb thiab cov txheej txheem pov tseg.

Thov nco ntsoov tias tsab xov xwm no tsuas yog ib qho kev piav qhia ntawm cov ntsiab lus hauv cov lus nug, thiab cov ntawv thov tshwj xeeb thiab kev ntsuas kev pheej hmoo yuav tsum tau ua nyob rau hauv ib qho chaw kuaj mob tshwj xeeb. Ua ntej siv cov tshuaj, thov nco ntsoov kawm cov ntaub ntawv tseem ceeb hauv kev nthuav dav thiab sab laj tus kws tshaj lij ua ntej.