N-Cbz-L-Leucine (CAS # 2018-66-8)
Risk thiab Safety
| Hazard Cov Cim | Xn – Ua phem |
| Risk Codes | R10 - Flammable R20/22 - Ua phem los ntawm kev nqus pa thiab yog tias nqos. R37/38 - Kab mob ua pa thiab tawv nqaij. R40 - Cov pov thawj txwv ntawm cov nyhuv carcinogenic R41 - Riam phom loj rau qhov muag R36/37/38 - Kab mob rau qhov muag, ua pa thiab tawv nqaij. R20/21/22 - Ua phem los ntawm kev nqus pa, tiv thaiv daim tawv nqaij thiab yog tias nqos. R67 - Vapors tuaj yeem ua rau qaug zog thiab kiv taub hau R63 - Muaj peev xwm tsim kev puas tsuaj rau tus menyuam hauv plab R19 - Tej zaum yuav tsim cov peroxides tawg |
| Kev nyab xeeb piav qhia | S16 - Khaws kom deb ntawm qhov chaw hluav taws xob. S26 - Thaum sib cuag nrog lub qhov muag, yaug tam sim ntawd nrog dej txaus thiab nrhiav kev kho mob. S36/37/39 - Hnav cov khaub ncaws tiv thaiv tsim nyog, hnab looj tes thiab tiv thaiv qhov muag / ntsej muag. S45 - Thaum muaj xwm txheej lossis yog tias koj tsis xis nyob, nrhiav kev kho mob tam sim ntawd (qhia daim ntawv lo thaum twg ua tau.) S36 - Hnav khaub ncaws tiv thaiv zoo. S36/37 - Hnav cov khaub ncaws tiv thaiv thiab hnab looj tes tsim nyog. S60 - Cov khoom no thiab nws lub thawv yuav tsum tau muab pov tseg raws li cov khoom pov tseg. |
| UN IDs | UN 1993 3/PG 3 |
| WGK Germany | 3 |
| RTECS | OH2921000 |
| HS Code | 29242990 ib |
N-Cbz-L-Leucine (CAS# 2018-66-8) Introduction
Cbz-L-leucine, lub npe tag nrho ntawm Boc-L-leucine (Boc stands rau dibutoxycarbonyl tiv thaiv pawg), yog ib qho amino acid derivative. Cov hauv qab no yog kev qhia txog nws qhov xwm txheej, kev siv, kev tsim khoom thiab cov ntaub ntawv kev nyab xeeb:
Zoo:
- Cov tsos: Dawb crystalline khoom
- Soluble: Soluble hauv ethanol, dimethylformamide (DMF) thiab dichloromethane
Siv:
- CBZ-L-Leucine yog ib feem siv cov amino acid tiv thaiv pab pawg uas tiv thaiv pawg hydroxyl ntawm leucine thaum lub sij hawm synthesis ntawm peptides los tiv thaiv nws los ntawm reacts nrog lwm cov reactants. Hauv peptide synthesis qhov twg ntau cov leucine seem yuav tsum tau qhia, Cbz-L-leucine tuaj yeem siv los tiv thaiv pawg hydroxyl ntawm leucine rau cov txheej txheem tom ntej.
- Leucine yog ib qho tseem ceeb amino acid uas ua lub luag haujlwm tseem ceeb hauv cov qauv protein thiab kev ua haujlwm.
Txoj kev:
- Kev npaj ntawm Cbz-L-leucine feem ntau tau txais los ntawm cov tshuaj tiv thaiv ntawm leucine nrog Boc-OSu (Boc-N-nitrocarbonyl-L-leucine). Hauv cov tshuaj tiv thaiv, Boc-OSu ua tus qhia txog pab pawg tiv thaiv thiab tau txais cov tshuaj tiv thaiv esterification nrog leucine los tsim Cbz-L-leucine.
Cov ntaub ntawv kev nyab xeeb:
- Cbz-L-leucine yog ib yam tshuaj thiab yuav tsum khaws cia kom deb ntawm qhov hluav taws kub thiab oxidants.
- Thaum siv, tsis txhob nqus nws cov plua plav lossis nkag mus rau ntawm daim tawv nqaij thiab qhov muag.
- Ua raws li cov kev coj noj coj ua uas muaj kev nyab xeeb thaum tuav thiab khaws cia, thiab hnav cov khoom tiv thaiv tus kheej tsim nyog xws li hnab looj tes kuaj thiab tiv thaiv qhov muag.
