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Tom ntej: NN-Bis 9-fluorenylmethyloxycarbonyl-L-histidine CAS 98929-98-7

Chemical Property:

Molecular Formula C36H29N3O6
Molar Mass 599.63 ib
Qhov ntom 1.38 ± 0.1 g / cm3 (Tshaj tawm)
Melting Point 144-155 ° C
pKa 12.26 ± 0.46 (Tshaj tawm)
Kev cia khoom Muab ntim rau hauv qhuav, 2-8 ° C
Refractive Index 1.696 ib

Product Detail

Khoom cim npe

Risk thiab Safety

Kev nyab xeeb piav qhia S22 - Tsis txhob nqus plua plav.
S24/25 - Tsis txhob sib cuag nrog daim tawv nqaij thiab qhov muag.
HS Code 29242990 ib

Taw qhia

N(alpha), N(im)-di-fmoc-L-histidine(N(alpha), N(im)-di-fmoc-L-histidine) yog ib tug compound tau los ntawm cov tshuaj tiv thaiv ntawm 9-fluorenecinol thiab L. -histidine. Nws cov tshuaj formula yog C42H38N4O8 thiab nws cov txheeb ze molecular loj yog 722.78g/mol.N(alpha), N(im)-di-fmoc-L-histidine yog ib tug compound uas tiv thaiv cov amino acids thiab yog dav siv nyob rau hauv organic synthesis thiab biochemical tshuaj. . Nws yog tsuas yog siv los tswj cov qauv protein thiab kev ua haujlwm, nrog rau kev nthuav dav thiab txhim kho daim ntawv thov ntau yam ntawm polypeptide chains. Qhov kev sib xyaw no tau siv dav hauv cov txheej txheem sib xyaw ua ke rau kev hloov kho N-terminus thiab histidine residues ntawm peptide thiab protein molecules.

Txoj kev npaj N(alpha), N(im)-di-fmoc-L-histidine feem ntau muaj peb kauj ruam. Ua ntej, ethylene glycol dimethyl ether thiab diazotoluene tau tshwm sim nyob rau hauv lub catalysis ntawm cuprous chloride los ua ke 9-fluorenmethanol. Tom qab ntawd, 9-fluorenecinol thiab L-histidine tau tshwm sim nyob rau hauv acidic tej yam kev mob kom tau N(alpha), N(im)-di-fmoc-L-histidine. Thaum kawg, cov khoom ntshiab yog tau los ntawm crystallization thiab purification cov kauj ruam.

Hais txog cov ntaub ntawv kev nyab xeeb, N(alpha), N(im)-Tsis muaj ntau cov ntaub ntawv tshawb fawb txog kev nyab xeeb ntawm di-fmoc-L-histidine, yog li yuav tsum tau ceev faj. Thaum siv hauv chav kuaj, yuav tsum muaj kev ntsuas kev nyab xeeb tsim nyog, suav nrog kev hnav cov cuab yeej tiv thaiv tsim nyog, xws li cov hnab looj tes hauv chav kuaj thiab tsom iav, thiab tsis txhob sib cuag nrog daim tawv nqaij thiab qhov muag. Nyob rau tib lub sijhawm, nws yuav tsum tau muab cia rau hauv lub thawv qhuav, qhov cua thiab kaw, kom deb ntawm cov khoom siv hluav taws xob thiab cov khoom siv hluav taws xob. Rau cov ncauj lus kom ntxaws txog kev nyab xeeb, nws raug nquahu kom sab laj cov ntaub ntawv ntsig txog lossis nrog tus kws tshaj lij.


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