Lub khw muag tshuaj nyob sab Europe tab tom muaj kev hloov pauv tseem ceeb, uas tau tsav los ntawm kev xav tau ntau ntxiv rau kev kho tshiab thiab kev txhim kho txuas ntxiv ntawm cov txheej txheem tsim tshuaj. Ib tug ntawm cov tseem ceeb players nyob rau hauv daim teb no yog 2-aminobenzonitrile, ib tug tseem ceeb tshuaj intermediate uas tau attracted ntau xim vim nws lub luag hauj lwm nyob rau hauv lub synthesis ntawm lapatinib, lub hom phiaj kev kho mob siv feem ntau los kho mob cancer ntawm lub mis.
2-Aminobenzonitrile, tshuaj identifier1885-29-6, yog ib qho tshuaj tsw qab uas yog lub tsev tseem ceeb hauv kev tsim khoom ntawm ntau yam tshuaj. Nws cov khoom siv tshuaj lom neeg tshwj xeeb ua rau nws yog ib qho tseem ceeb hauv kev sib txuas ntawm lapatinib, dual tyrosine kinase inhibitor uas lub hom phiaj ntawm epidermal growth factor receptor (EGFR) thiab human epidermal growth factor receptor 2 (HER2). Cov txheej txheem ntawm kev ua no tshwj xeeb tshaj yog muaj txiaj ntsig zoo rau cov neeg mob uas muaj HER2-zoo mob qog noj ntshav mis, muab txoj hauv kev kho mob uas txo qis kev puas tsuaj rau cov hlwb noj qab haus huv piv rau cov tshuaj khomob ib txwm muaj.
Nyob rau hauv xyoo tas los no, qhov kev thov rau lapatinib tau nce zuj zus nrog qhov tshwm sim ntawm kev mob qog noj ntshav mis thiab nce kev paub txog qhov tseem ceeb ntawm cov tshuaj kho tus kheej. Yog li ntawd, kev ua lag luam rau cov tshuaj intermediates, suav nrog 2-aminobenzonitrile, tau nthuav dav sai. Cov tuam txhab tshuaj European tau nqis peev ntau hauv kev tshawb fawb thiab kev txhim kho los txhim kho kev ua tau zoo ntawm lapatinib ntau lawm, uas ua rau muaj kev thov rau cov khoom lag luam zoo.
Ib qho ntawm cov ntsiab lus tseem ceeb cuam tshuam rau European 2-aminobenzonitrile kev ua lag luam yog thaj tsam kev tswj hwm nruj. Lub Koom Haum Saib Xyuas Tshuaj European (EMA) tau teeb tsa cov lus qhia nruj rau kev tsim khoom thiab kev tswj xyuas cov tshuaj nruab nrab, kom ntseeg tau tias tsuas yog cov qauv siab tshaj plaws tau ua tiav. Txoj cai tswjfwm no tsis yog tsuas yog tiv thaiv tus neeg mob kev nyab xeeb xwb tab sis kuj txhawb kev tsim kho tshiab hauv kev lag luam vim cov tuam txhab siv zog ua raws li cov qauv no thaum tsim cov txheej txheem tshiab thiab txhim kho hluavtaws.
Tsis tas li ntawd, kev ua lag luam nyob sab Europe yog tus cwj pwm los ntawm kev loj hlob inclination rau sustainability thiab ntsuab chemistry. Cov chaw tsim tshuaj lag luam tau nce ntxiv nrhiav cov txheej txheem zoo ib puag ncig los tsim cov khoom nruab nrab xws li 2-aminobenzonitrile. Qhov kev hloov pauv no yog tsav los ntawm kev tswj hwm kev kub ntxhov thiab cov neeg siv khoom xav tau rau kev coj ua ruaj khov. Cov tuam txhab lag luam tab tom tshawb nrhiav lwm txoj hauv kev sib txuas los txo cov khib nyiab thiab txo cov kev cuam tshuam ib puag ncig ntawm lawv txoj haujlwm, raws li cov hom phiaj dav dav ntawm European Green Deal.
Ntxiv nrog rau kev ruaj khov, European kev lag luam kws tshuaj tseem tab tom ntsib nthwv dej ntawm kev nce qib thev naus laus zis. Kev sib koom ua ke ntawm kev txawj ntse txawj ntse (AI) thiab kev kawm tshuab hauv cov txheej txheem kev txhim kho tshuaj yog hloov pauv txoj hauv kev tsim tshuaj intermediates. Cov thev naus laus zis no ua rau cov tuam txhab txhim kho lawv txoj kev siv hluavtaws, txo cov nqi tsim khoom, thiab ua kom lub sijhawm ua lag luam rau cov tshuaj tseem ceeb xws li lapatinib.
Raws li European kev lag luam tshuaj txuas ntxiv txhim kho, lub luag haujlwm ntawm cov neeg nruab nrab xws li 2-aminobenzonitrile yuav tseem ceeb heev. Kev tshawb fawb txuas ntxiv mus rau cov ntawv thov tshiab thiab cov txheej txheem hluavtaws zoo li yuav ua rau muaj kev hloov tshiab ntxiv hauv kev tsim cov lapatinib thiab lwm yam kev kho mob. Qhov no nyob rau hauv lem yuav txhim kho txoj kev kho mob rau cov neeg mob thiab pab txhawb rau tag nrho cov kev loj hlob nyob rau hauv European kev lag luam kws tshuaj.
Hauv cov ntsiab lus, kev sib tshuam ntawm kev tswj hwm kev ua raws cai, kev ruaj khov, thiab kev tsim kho thev naus laus zis yog tsim lub neej yav tom ntej ntawm European kev lag luam tshuaj. Raws li kev thov rau lapatinib thiab nws cov intermediates, xws li 2-aminobenzonitrile, txuas ntxiv nce, cov neeg muaj feem cuam tshuam thoob plaws kev lag luam yuav tsum hloov mus rau cov qauv no kom muaj kev sib tw thiab ua tau raws li cov kev xav tau ntawm cov neeg mob. Lub neej yav tom ntej ntawm cov tshuaj intermediates yog ci, thiab 2-aminobenzonitrile yog nyob rau hauv pem hauv ntej ntawm no dynamic toj roob hauv pes.
Post lub sij hawm: Dec-12-2024