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Papaverine Hydrochloride (CAS # 61-25-6)

Chemical Property:

Molecular Formula C20H22ClNO4
Molar Mass 375.85 ib
Melting Point 226 ° C (Lub Kaum Ob Hlis)
Boling Point 483.2 ° C ntawm 760 mmHg
Flash Point 172.2°C dej
Dej Solubility dawb do soluble
Solubility H2O: 25 mg/ml
Vapor Siab 5.01E-09mmHg ntawm 25 ° C
Qhov tshwm sim hmoov
Xim dawb
Merck 14.7019 Nws
BRN 3921435 ib
PH pH (20g / l, 25 ℃): 3.0 ~ 4.0
Kev cia khoom Amber Vial, tub yees
Kev ruaj ntseg Stable, tab sis tej zaum yuav lub teeb rhiab heev.
rhiab heev Lub teeb Sensitive
Siv Siv raws li vasodilator

Product Detail

Khoom cim npe

Risk Codes R22 - Ua phem yog tias nqos
R34 - Ua rau kub hnyiab
R11 - Cov nplaim hluav taws kub heev
Kev nyab xeeb piav qhia S22 - Tsis txhob nqus plua plav.
S45 - Thaum muaj xwm txheej lossis yog tias koj tsis xis nyob, nrhiav kev kho mob tam sim ntawd (qhia daim ntawv lo thaum twg ua tau.)
S36/37/39 - Hnav cov khaub ncaws tiv thaiv tsim nyog, hnab looj tes thiab tiv thaiv qhov muag / ntsej muag.
S26 - Thaum sib cuag nrog lub qhov muag, yaug tam sim ntawd nrog dej txaus thiab nrhiav kev kho mob.
S16 - Khaws kom deb ntawm qhov chaw hluav taws xob.
UN IDs UN 1544 6.1/PG 3
WGK Germany 1
RTECS NW8575000
FLUKA BRAND F CODE 8
TSCA Yog lawm
HS Code 29391900 ib
Hazard Class 6.1
Packing Group III
Toxicity LD50 hauv nas, nas (mg/kg): 27.5, 20 iv; 150, 370 sc (Levis)

 

 

Papaverine Hydrochloride (CAS # 61-25-6)

Papaverine hydrochloride, CAS naj npawb 61-25-6, yog ib qho tseem ceeb hauv kev lag luam tshuaj.
Los ntawm qhov pom ntawm cov khoom siv tshuaj, nws yog hydrochloride daim ntawv ntawm papaverine, thiab cov qauv tshuaj txiav txim siab nws cov khoom. Kev npaj ntawm atoms thiab kev npaj cov tshuaj bonds nyob rau hauv cov qauv molecular muab nws tshwj xeeb stability thiab reactivity. Cov tsos mob feem ntau yog dawb mus rau lub teeb daj crystalline hmoov, uas yog qhov zoo rau kev ua, khaws cia thiab kev thauj mus los ntawm cov tshuaj. Nyob rau hauv cov nqe lus ntawm solubility, nws muaj ib tug me ntsis solubility nyob rau hauv dej, thiab sib txawv acid-base ib puag ncig thiab kub tej yam kev mob yuav cuam tshuam rau nws solubility yam ntxwv, uas yog ib qho tseem ceeb rau kev tsim cov tshuaj, kev loj hlob ntawm ntau npaum li cas cov ntaub ntawv, thiab yuav ua li cas los xyuas kom meej uniformity. dispersion ntawm cov tshuaj thaum txhaj tshuaj thiab qhov ncauj npaj.
Nyob rau hauv cov nqe lus ntawm pharmacological kev ua tau zoo, Papaverine Hydrochloride belongs rau cov chav kawm ntawm cov leeg nqaij relaxants. Nws tsuas yog ua rau cov leeg nqaij du ntawm cov hlab ntsha, plab hnyuv, kab mob plab thiab lwm qhov chaw, thiab txhawb nqa cov leeg du los ntawm kev cuam tshuam nrog cov txheej txheem xws li kev thauj mus los ntawm calcium ion intracellular. Clinically, nws yog feem ntau siv los kho ischemia los ntawm vasospasm, xws li mob taub hau thiab kiv taub hau los ntawm cerebral vasospasm, uas tuaj yeem txhim kho cov ntshav ncig hauv zos; Nws kuj tseem muaj txiaj ntsig zoo rau qhov mob plab thiab biliary colic tshwm sim los ntawm plab hnyuv spasm, txo qhov mob ntawm cov neeg mob.
Txawm li cas los xij, zoo li feem ntau cov tshuaj, nws yog ib qho tseem ceeb uas yuav tau ua raws li koj tus kws kho mob cov lus qhia thaum siv lawv. Vim muaj kev sib txawv ntawm lub cev thiab cov kab mob hauv lub cev ntawm tus neeg mob, cov kws kho mob yuav tsum ntsuas tus neeg mob lub hnub nyoog, lub siab thiab lub raum kev ua haujlwm, lwm yam tshuaj raug noj thiab lwm yam, thiab txiav txim siab qhov koob tshuaj, txoj hauv kev ntawm kev tswj hwm thiab kev siv tshuaj, yog li ntawd. los xyuas kom meej tias cov tshuaj muaj kev nyab xeeb thiab siv tau zoo, thiab pab tus neeg mob zoo. Nrog rau kev nce qib ntawm kev tshawb fawb tshawb fawb, kev tshawb fawb thiab kev txhim kho ntawm cov ntawv siv tshuaj tshiab thiab kev ua kom zoo ntawm cov tshuaj sib xyaw ua ke nyob ib puag ncig nws kuj ua kom sov.


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