(S)-N-ALPHA-T-BUTYLOXYCARBONYL-PYROGLUTAMIC ACID T-BUTYL ESTER (CAS # 91229-91-3)
Taw qhia
di-tert-butyl (2S)-5-oxopyrrolidine-1,2-dicarboxylate yog cov tshuaj uas nws cov tshuaj formula C14H23NO6. Cov hauv qab no yog cov lus piav qhia ntawm cov khoom, kev siv, kev npaj thiab kev nyab xeeb cov ntaub ntawv ntawm lub compound:
Xwm:
-Cov tsos mob: di-tert-butyl (2S)-5-oxopyrrolidine-1,2-dicarboxylate yog xim tsis muaj xim rau dawb crystalline khoom.
-Solubility: Nws yog soluble hauv cov kuab tshuaj organic xws li ethanol, methanol thiab dimethyl sulfoxide.
-Melting point: Lub compound melts ntawm 104-105 ° C.
Siv:
di-tert-butyl (2S)-5-oxopyrrolidine-1,2-dicarboxylate yog ib qho kev siv cov amino acid derivative, feem ntau siv los ua cov reagent hauv cov organic synthesis. Nws tuaj yeem siv los tsim cov khoom siv roj ntsha lom neeg, xws li tshuaj thiab cov ntaub ntawv polymer.
Txoj kev:
Kev npaj ntawm di-tert-butyl (2S)-5-oxopyrrolidine-1,2-dicarboxylate feem ntau yog ua los ntawm cov kauj ruam hauv qab no:
1. Dissolve pyroglutamic acid tert-butyl ester nyob rau hauv qhuav dimethyl sulfoxide.
2. Ib qho tsim nyog ntawm N, N'-dihydroxyethyl isopropanamide tau ntxiv thiab cov tshuaj tiv thaiv sib xyaw tau txias kom qis dua 0 ° C.
3. Ntxiv di-tert-butyl carbonate maj mam thaum tswj qhov kub ntawm cov tshuaj tiv thaiv hauv qab 0 ° C.
4. Tom qab ua tiav cov tshuaj tiv thaiv, cov tshuaj tiv thaiv sib tov ntxiv rau hauv dej los tsim cov khoom precipitate ntawm di-tert-butyl (2S)-5-oxopyrrolidine-1,2-dicarboxylate.
5. Cov khoom kawg tau txais los ntawm cov kauj ruam ntawm crystallization, pom thiab ziab.
Cov ntaub ntawv kev nyab xeeb:
di-tert-butyl (2S)-5-oxopyrrolidine-1,2-dicarboxylate yuav tsum tau siv thiab ua raws li cov kev coj ua nyab xeeb kom tsis txhob raug rau ntawm daim tawv nqaij, qhov muag thiab nqus tau pa. Tsis tas li ntawd, nws yuav tsum tau muab cia rau hauv qhov chaw qhuav, txias thiab deb ntawm hluav taws thiab oxidants. Rau cov ntaub ntawv kev nyab xeeb tshwj xeeb, xa mus rau Chemical Safety Data Sheet (MSDS) lossis cov ntaub ntawv cuam tshuam los ntawm tus muag khoom.
