Tetrahydroppaverine hydrochloride (CAS # 6429-04-5)
Tetrahydropapaverine hydrochloride (CAS # 6429-04-5) yog ib qho kev sib xyaw ua ke uas tuav qhov tseem ceeb hauv thaj chaw xws li tshuaj.
Visually, nws feem ntau tshwm raws li cov hmoov dawb crystalline hmoov nrog cov khoom zoo-lub xeev ruaj khov, ua rau nws yooj yim rau khaws thiab thauj. Nyob rau hauv cov nqe lus ntawm solubility, nws muaj ib tug tej yam degree ntawm solubility nyob rau hauv dej, uas tso cai rau nws yuav tsum tau zoo dispersed nyob rau hauv aqueous xov xwm thaum ua lwm yam kev npaj. Nyob rau tib lub sijhawm, nws tseem tuaj yeem nthuav tawm qee cov yam ntxwv solubility hauv qee cov kuab tshuaj organic, xws li methanol, ethanol thiab lwm yam cawv organic solvents.
Los ntawm cov qauv tshuaj ntsuam xyuas, nws cov qauv molecular muaj ib qho tshwj xeeb nitrogen-muaj heterocyclic moiety, uas endows nws nrog ib tug tshwj xeeb pharmacological kev ua ntawm lub hauv paus. Nws tuaj yeem cuam tshuam nrog qee lub hom phiaj lom neeg hauv lub cev, xws li cov receptors tshwj xeeb, cov enzymes, thiab lwm yam, thiab ua rau muaj kev cuam tshuam txog kev noj qab haus huv ntawm lub cev. Ntxiv mus, lub xub ntiag ntawm hydrochloric acid tsis tsuas yog nce lub solubility ntawm tag nrho cov compound nyob rau hauv dej, tab sis kuj muaj feem xyuam rau nws cov tshuaj stability thiab muaj feem xyuam rau cov khoom xws li tshuaj metabolism mus rau ib tug tej yam kev mob.
Nyob rau hauv daim ntawv thov teb, nws yog tsuas yog siv nyob rau hauv kev lag luam kws tshuaj raws li ib tug zoo tshuaj muaj, feem ntau yog siv los txo cov kab mob xws li vascular spasm. Los ntawm kev so cov leeg nqaij leeg thiab txhim kho cov ntshav ncig hauv zos, nws muaj txiaj ntsig zoo rau kev kho mob ntawm qee cov kab mob plawv thiab cerebrovascular, thiab tuaj yeem pab txo cov tsos mob tsis xis nyob los ntawm vascular spasm thiab txhim kho lub neej zoo ntawm cov neeg mob.
Thaum khaws cia thiab siv, nws yog ib qho tseem ceeb uas yuav tsum tau muab tso rau hauv qhov chaw kaw thiab qhuav kom tsis txhob ya raws, vim tias ya raws yuav cuam tshuam rau nws cov tshuaj lom neeg ruaj khov thiab crystalline xeev. Nyob rau tib lub sijhawm, nws yuav tsum tau muab khaws cia rau hauv cov xwm txheej kub, kom deb ntawm qhov kub thiab txias ib puag ncig, tiv thaiv kom tsis txhob decomposition thiab denaturation, thiab nruj me ntsis ua raws li cov kev cai cuam tshuam rau kev khaws tshuaj thiab kev siv tshuaj kom muaj kev nyab xeeb thiab siv tau zoo.
